tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Base Information

Chemical Name:tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate
CAS No.:906651-54-5
Molecular Formula:C₄₅H₇₁NO₁₀
Molecular Weight:786.059
Hs Code.:

tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Synonyms:tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Suppliers and Price of tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

There total 6 articles about tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-2-(2-((tertbutyldimethylsilyl)oxy)ethyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxyundec-4-enoate

: 906651-54-5
tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

Reference yield:

: 16874-12-7,87553-74-0
Tyr(tBu)

: 906651-54-5
tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: N,N-dimethyl-formamide / 1 h / 25 °C / Large scale

2.1: potassium carbonate / water / 1 h / 25 °C / Large scale

3.1: hydrogenchloride / ethyl acetate / 2 h / 25 °C / Large scale

4.1: potassium hydrogensulfate / water; ethyl acetate / 0.5 h / 20 °C / Large scale

4.2: 4 h / 20 °C / Large scale

5.1: tetrabutyl ammonium fluoride; acetic acid / 3 h / 20 °C / Large scale

With hydrogenchloride; potassium hydrogensulfate; tetrabutyl ammonium fluoride; potassium carbonate; acetic acid; In water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/acs.oprd.7b00383

Reference yield:

: 827036-34-0
tert-butyl (S)-3-(4-(but-2-yn-1-yloxy)phenyl)-2-((tertbutoxycarbonyl)amino)propanoate

: 906651-54-5
tert-butyl (2S,3S,E)-3-(((S)-3-(4-(but-2-yn-1-yloxy)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)-11-(2-heptyl-1,3-dioxolan-2-yl)-2-hydroxy-2-(2-hydroxyethyl)undec-4-enoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogenchloride / ethyl acetate / 2 h / 25 °C / Large scale

2.1: potassium hydrogensulfate / water; ethyl acetate / 0.5 h / 20 °C / Large scale

2.2: 4 h / 20 °C / Large scale

3.1: tetrabutyl ammonium fluoride; acetic acid / 3 h / 20 °C / Large scale

With hydrogenchloride; potassium hydrogensulfate; tetrabutyl ammonium fluoride; acetic acid; In water; ethyl acetate;
DOI:10.1021/acs.oprd.7b00383