1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester

Base Information

• Chemical Name: 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester
• CAS No.: 916139-84-9
• Molecular Formula: C₄₄H₆₀O₁₀
• Molecular Weight: 748.954
• Mol file: 916139-84-9.mol

Synonyms:1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester

Chemical Property of 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester

There total 4 articles about 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

9-acetoxy-8-acetoxymethyl-1-isopropenyl-5a,5b,8,11a-tetramethyl-eicosahydro-cyclopenta[a]chrysene-3a-carboxylic acid 2-hydroxy-ethyl ester (916139-31-6) + phthalic anhydride (85-44-9) → 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester (916139-84-9)

Guidance literature:

9-acetoxy-8-acetoxymethyl-1-isopropenyl-5a,5b,8,11a-tetramethyl-eicosahydro-cyclopenta[a]chrysene-3a-carboxylic acid 2-hydroxy-ethyl ester; phthalic anhydride; With dmap; In dichloromethane; at 20 ℃; for 10h;

With hydrogenchloride; In dichloromethane; water;

DOI:10.3390/molecules17088832

Reference yield:

23-hydroxybetulinic acid (85999-40-2) → 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester (916139-84-9)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / 20 °C

2: oxalyl dichloride / dichloromethane / 4 h / 20 °C

3: dichloromethane / 8 h / 20 °C

4: dmap / dichloromethane / 10 h / 20 °C

With pyridine; dmap; oxalyl dichloride; In dichloromethane;

DOI:10.3390/molecules17088832

Reference yield:

3,23-diacetoxylup-20(29)-en-28-oic acid (85999-41-3) → 1,2-xylenedioic acid 1-[2-[(3β,23-diacetoxylup-20(29)-en-28-oyl)oxy]ethyl] ester (916139-84-9)

Guidance literature:

Multi-step reaction with 3 steps

1: oxalyl dichloride / dichloromethane / 4 h / 20 °C

2: dichloromethane / 8 h / 20 °C

3: dmap / dichloromethane / 10 h / 20 °C

With dmap; oxalyl dichloride; In dichloromethane;

DOI:10.3390/molecules17088832

upstream raw materials:

9-acetoxy-8-acetoxymethyl-1-isopropenyl-5a,5b,8,11a-tetramethyl-eicosahydro-cyclopenta[a]chrysene-3a-carboxylic acid 2-hydroxy-ethyl ester

phthalic anhydride

23-hydroxybetulinic acid

3,23-diacetoxylup-20⁽²⁹⁾-en-28-oic acid