S,S-Dimethyl sulfoximine

Base Information

• Chemical Name: S,S-Dimethyl sulfoximine
• CAS No.: 1520-31-6
• Molecular Formula: C2H7 N O S
• Molecular Weight: 93.1497
• Hs Code.: 2925290090
• European Community (EC) Number: 696-368-0
• DSSTox Substance ID: DTXSID40164933
• Nikkaji Number: J858.531H
• Wikidata: Q72472088
• Mol file: 1520-31-6.mol

Synonyms:S,S-dimethyl sulfoximine

Chemical Property of S,S-Dimethyl sulfoximine

Chemical Property:

• Vapor Pressure: 34.4mmHg at 25°C
• Melting Point: 56 °C
• Refractive Index: 1.454
• Boiling Point: 105.4°Cat760mmHg
• Flash Point: 17.5°C
• PSA: 49.30000
• Density: 1.13g/cm³
• LogP: 1.25820
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 93.02483502
• Heavy Atom Count: 5
• Complexity: 103

Purity/Quality:

98%,99%, ^*data from raw suppliers

(Dimethanesulfinylidene)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=N)(=O)C
• Uses: (dimethanesulfinylidene)amine is a useful reactant for the synthesis of N-?sulfenyl sulfoximines derivatives and as well as useful for N-?thioetherification of NH-?sulfoximines.

Technology Process of S,S-Dimethyl sulfoximine

There total 11 articles about S,S-Dimethyl sulfoximine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-acetyl-S,S-dimethylsulfoximine (748142-64-5) → dimethylsulfoximine (1520-31-6)

Guidance literature:

With hydrogenchloride; water; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/ejoc.201500855

Reference yield: 93.0%

S,S-dimethyl-N-(4-tolylsulfonyl)sulfoximine (22236-45-9) → dimethylsulfoximine (1520-31-6)

Guidance literature:

With anthracene; sodium; In 1,2-dimethoxyethane; at 0 ℃;

DOI:10.1021/jo00265a051

Reference yield: 87.0%

dimethyl sulfoxide (67-68-5,8070-53-9) → dimethylsulfoximine (1520-31-6)

Guidance literature:

With sodium azide; sulfuric acid; In dichloromethane; at 0 - 35 ℃;

upstream raw materials:

dimethylsulfide

dimethyl sulfoxide

S,S-dimethylsulfodiimide

S,S-dimethyl-N-(4-tolylsulfonyl)sulfoximine

Downstream raw materials:

C₉H₁₀Cl₂N₂O₂S

C₉H₁₁N₃O₄S

S,S-dimethyl-N-[(4-nitrophenyl)carbamoyl]sulphoximide

N-(benzoyl)-S,S-dimethylsulfoximine

Refernces

• 1、 Whitehead,Bentley. "-". . p. 1572. Retrieved 1952.
• 2、 Zupanc, An?e,Jereb, Marjan. "One-Pot Synthesis of N-Iodo Sulfoximines from Sulfides". . p. 5991 - 6000. Retrieved 2021/05/05.
• 3、 Zhao, Peng,Wu, Xia,Geng, Xiao,Wang, Can,Zhou, You,Wu, Yan-Dong,Wu, An-Xin. "I2/PhI(OAc)2 Copromoted Amination Reaction: Synthesis of α-Dicarbonylsulfoximine Derivatives by Incorporating an Intact Dimethyl Sulfoxide". supporting information. p. 8322 - 8329. Retrieved 2019/06/27.