ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

Base Information

Chemical Name:ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate
CAS No.:1260022-76-1
Molecular Formula:C₂₇H₃₁N₃O₄
Molecular Weight:461.561
Hs Code.:

Synonyms:ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

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Chemical Property of ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

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Technology Process of ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

There total 1 articles about ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 258273-31-3
3-cyano-4-isopropoxybenzoic acid

: 1260022-71-6
ethyl 4-{3-[(Z)-(hydroxyamino)(imino)methyl]-2-propylphenyl}butanoate

: 1260022-76-1
ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

Guidance literature:: 3-cyano-4-isopropoxybenzoic acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; In tetrahydrofuran; at 20 ℃; for 1h;

ethyl 4-{3-[(Z)-(hydroxyamino)(imino)methyl]-2-propylphenyl}butanoate; In tetrahydrofuran; at 20 ℃; for 1h;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 120 ℃; for 2h; Sealed; Microwave irradiation;

Reference yield:

: 1260022-76-1
ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate

: 1260021-21-3
4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoic acid

Guidance literature:: ethyl 4-[3-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2-propylphenyl]butanoate; With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; water; pH=6;