2-METHYL-1-PHENYL-1H-BENZOIMIDAZOLE

Base Information

• Chemical Name: 2-METHYL-1-PHENYL-1H-BENZOIMIDAZOLE
• CAS No.: 1484-39-5
• Molecular Formula: C14H12 N2
• Molecular Weight: 208.263
• Hs Code.: 2933990090
• Mol file: 1484-39-5.mol

Synonyms:Benzimidazole,2-methyl-1-phenyl- (7CI,8CI); 1-Phenyl-2-methylbenzimidazole;2-Methyl-1-phenylbenzimidazole

Chemical Property of 2-METHYL-1-PHENYL-1H-BENZOIMIDAZOLE

Chemical Property:

• PSA: 17.82000
• LogP: 3.33390

Purity/Quality:

97% ^*data from raw suppliers

2-Methyl-1-phenyl-1H-benzimidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-1-PHENYL-1H-BENZOIMIDAZOLE

There total 60 articles about 2-METHYL-1-PHENYL-1H-BENZOIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N'-(2-iodophenyl)-N-phenylacetimidamide (1261604-58-3) → 2-methyl-1-phenyl-1H-benzimidazole (1484-39-5)

Guidance literature:

With copper(I) oxide; potassium carbonate; N,N`-dimethylethylenediamine; In water; at 100 ℃; for 30h; Sealed tube;

DOI:10.1021/jo1021426

Reference yield: 99.0%

N-phenylacetamidine (14277-00-0) + 2,3-dibromobenzene (583-53-9) → 2-methyl-1-phenyl-1H-benzimidazole (1484-39-5)

Guidance literature:

With palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; In toluene; at 140 ℃; for 24h; regiospecific reaction; Molecular sieve; Inert atmosphere;

DOI:10.1021/ol202807d

Reference yield: 97.0%

N'-(2-fluorophenyl)-N-phenylacetimidamide (1519051-02-5) → 2-methyl-1-phenyl-1H-benzimidazole (1484-39-5)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; at 120 ℃; for 16h; Time; Inert atmosphere; Sealed tube;

DOI:10.1021/ol403414v

upstream raw materials:

N-acetyl-N-phenyl-o-nitroaniline

4-benzylidene-2-methyl-2-oxazolin-5-one

N-phenyl-1,2-benzenediamine

(Z)-2-methyl-4-(4-methylbenzylidene)oxazol-5(4H)-one

Downstream raw materials:

2-benzhydryl-1-phenyl-1H-benzoimidazole

1-phenyl-1H-benzo[d]imidazole-2-carbaldehyde

2-(p-Nitrophenyl)-4-phenylpyrrolo<1,2-a>benzimidazole

1-Phenyl-2-methyl-3-(p-nitrophenacyl)benzimidazolium Bromide