L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO

Base Information

• Chemical Name: L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO
• CAS No.: 1482-98-0
• Molecular Formula: C4H10 N2 O2 . Cl H
• Molecular Weight: 154.59534
• Hs Code.: 2922499990
• Mol file: 1482-98-0.mol

Synonyms:Butanoicacid, 2,4-diamino-, monohydrochloride, (S)- (9CI); Butyric acid, 2,4-diamino-,monohydrochloride, L- (8CI); (S)-2,4-Diaminobutanoic acid monohydrochloride; L-a,g-Diaminobutyric acid monohydrochloride

Chemical Property of L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO

Chemical Property:

• Vapor Pressure: 2.4E-05mmHg at 25°C
• Melting Point: 193 °C (dec.)(lit.)
• Boiling Point: 334.6°Cat760mmHg
• Flash Point: 156.2°C
• PSA: 89.34000
• Density: g/cm³
• LogP: 0.94970

Purity/Quality:

99.3% ^*data from raw suppliers

L-2,4-Diaminobutyricacidhydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 37/38-41
• Safety Statements: 26-36/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO

There total 6 articles about L-2 4-DIAMINOBUTYRIC ACID MONOHYDRO-CHLO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N-γ-acetyl-L-2,4-diaminobutyrate (1190-46-1) → L-2,4-diaminobutyric acid monohydrochloride (1482-98-0)

Guidance literature:

With hydrogenchloride; In water; Reflux;

Reference yield: 89.0%

Nα,Nγ-bis(t-butoxycarbonyl)-L-α,γ-butyric acid (34404-27-8,752986-92-8) → (S)-2,4-diaminobutyric acid dihydrochloride (1482-98-0,1883-09-6,6970-28-1,19391-83-4,26889-08-7,40149-78-8,57538-26-8,65427-54-5,66837-03-4,89700-93-6,101854-78-8,127531-11-7)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/j.tetlet.2006.11.033

Reference yield: 80.0%

(S)-2,4-diamino-butyric acid ; hydrobromide (73143-97-2) → L-2,4-diaminobutyric acid monohydrochloride (1482-98-0)

Guidance literature:

With acetyl chloride; In methanol; at 0 ℃;

DOI:10.1016/S0040-4039(00)60152-1

upstream raw materials:

(S)-3-Cyano-2-[(1R,2R,5R)-2-hydroxy-2,6,6-trimethyl-bicyclo[3.1.1]hept-(3E)-ylideneamino]-propionic acid ethyl ester

N^α,N^γ-bis(t-butoxycarbonyl)-L-α,γ-butyric acid

(R)-2,4-Diamino-butyric acid ethyl ester; hydrochloride

(S)-2,4-diamino-butyric acid ; hydrobromide

Downstream raw materials:

DPAB-L-DBA (trans)

⁽⁵⁾-(+)(D)-N,N'-Ditosyl-2,4-diamino-butanol

(R)-2,4-bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)butanoic acid

(S)-2,4-bis(((benzyloxy)carbonyl)amino)butanoic acid

Refernces

• 1、 Ma, Sang-ho,Yoon, Doo Ha,Ha, Hyun-Joon,Lee, Won Koo. "Preparation of enantiopure 2-acylazetidines and their reactions with chloroformates". . p. 269 - 271. Retrieved 2007/10/03.
• 2、 Solladie-Cavallo, A.,Simon, M. C.. "ENANTIOSELECTIVE SYNTHESIS OF OPTICALLY PURE NATURAL S(+) OR UNNATURAL R(-) DABA". . p. 6011 - 6014. Retrieved 2007/10/02.