5-Methyl-1H-indole-2-carbaldehyde

Base Information

Chemical Name:5-Methyl-1H-indole-2-carbaldehyde
CAS No.:1463-60-1
Molecular Formula:C10H9 N O
Molecular Weight:159.18456
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20480300
Wikidata:Q82314992
Mol file:1463-60-1.mol

Synonyms:5-Methyl-1H-indole-2-carbaldehyde;1463-60-1;1H-Indole-2-carboxaldehyde, 5-methyl-;1H-Indole-2-carboxaldehyde, 5-methyl- (9CI);SCHEMBL5379757;DTXSID20480300;BAA46360;1h-indole-2-carboxaldehyde,5-methyl-;AKOS003657973;BS-49452;BB 0220027;CS-0093951;D75515;A884531

Suppliers and Price of 5-Methyl-1H-indole-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Methyl-1H-indole-2-carbaldehyde
10mg
$ 60.00

Medical Isotopes, Inc.
5-Methyl-1H-indole-2-carbaldehyde 95+%
1 g
$ 990.00

Matrix Scientific
5-Methyl-1H-indole-2-carbaldehyde
500mg
$ 184.00

Crysdot
5-Methyl-1H-indole-2-carbaldehyde 95+%
10g
$ 842.00

Crysdot
5-Methyl-1H-indole-2-carbaldehyde 95+%
5g
$ 559.00

Crysdot
5-Methyl-1H-indole-2-carbaldehyde 95+%
25g
$ 1409.00

Chemenu
5-Methyl-1H-indole-2-carbaldehyde 95%
25g
$ 1683.00

Chemenu
5-Methyl-1H-indole-2-carbaldehyde 95%
5g
$ 655.00

Chemenu
5-Methyl-1H-indole-2-carbaldehyde 95%
1g
$ 337.00

Chemenu
5-Methyl-1H-indole-2-carbaldehyde 95%
10g
$ 935.00

Total 18 raw suppliers

Chemical Property of 5-Methyl-1H-indole-2-carbaldehyde

Chemical Property:

PSA：32.86000
LogP:2.28880
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:159.068413911
Heavy Atom Count:12
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-1H-indole-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)NC(=C2)C=O

Technology Process of 5-Methyl-1H-indole-2-carbaldehyde

There total 7 articles about 5-Methyl-1H-indole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 55795-87-4
(5-methyl-1H-indol-2-yl)methanol

: 1463-60-1
5-Methylindole-2-carboxaldehyde

Guidance literature:: With manganese(IV) oxide; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1039/d1gc02570h

Reference yield:

: 56813-19-5
6-methylindol-2-ylmethanol

: 1463-60-1
5-Methylindole-2-carboxaldehyde

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; at 10 - 20 ℃; for 2h;
DOI:10.1055/s-0034-1380506

Reference yield:

: 16382-15-3
5-methyl-1H-indole-2-carboxylic acid ethyl ester

: 1463-60-1
5-Methylindole-2-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 3.5 h / 0 °C / Inert atmosphere; Schlenk technique

2: manganese(IV) oxide / dichloromethane / 12 h / 10 - 20 °C / Inert atmosphere; Schlenk technique

With manganese(IV) oxide; lithium aluminium tetrahydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/acs.orglett.9b01624