benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate

Base Information

• Chemical Name: benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate
• CAS No.: 1440976-13-5
• Molecular Formula: C₁₇H₁₅N₃O₃
• Molecular Weight: 309.324
• Mol file: 1440976-13-5.mol

Synonyms:benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate

Chemical Property of benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate

There total 3 articles about benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

3-chloro-1-methyl-1H-quinoxalin-2-one (55687-06-4) + O-benzyl carbamate (621-84-1) → benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate (1440976-13-5)

Guidance literature:

With palladium diacetate; potassium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 90 ℃; for 2h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c3ob40338f

Reference yield: 46.0%

1-methyl-2(1H)-quinoxalinone (6479-18-1) + C13H8Cl4N2O3 → benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate (1440976-13-5)

Guidance literature:

With eosin y; In dichloromethane; at 20 ℃; for 24h; Schlenk technique; Irradiation;

DOI:10.1021/acs.orglett.1c00064

Reference yield:

Benzyl N-hydroxycarbamate (3426-71-9) → benzyl N-(4-methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)carbamate (1440976-13-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dichloromethane / 4 h / 20 °C

2: eosin y / dichloromethane / 24 h / 20 °C / Schlenk technique; Irradiation

With potassium carbonate; eosin y; In dichloromethane;

DOI:10.1021/acs.orglett.1c00064

upstream raw materials:

3-chloro-1-methyl-1H-quinoxalin-2-one

O-benzyl carbamate

1-methyl-2(1H)-quinoxalinone

Benzyl N-hydroxycarbamate