C₅₉H₁₀₃N₇O₁₈

Base Information

• Chemical Name: C₅₉H₁₀₃N₇O₁₈
• CAS No.: 1259518-83-6
• Molecular Formula: C₅₉H₁₀₃N₇O₁₈
• Molecular Weight: 1198.5
• Mol file: 1259518-83-6.mol

Synonyms:C₅₉H₁₀₃N₇O₁₈

Chemical Property of C₅₉H₁₀₃N₇O₁₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₉H₁₀₃N₇O₁₈

There total 9 articles about C₅₉H₁₀₃N₇O₁₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C52H90N6O17 (1259518-82-5) + methyl 6-aminocaproate hydrochloride (1926-80-3) → C59H103N7O18 (1259518-83-6)

Guidance literature:

With (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1021/jal086112

Reference yield:

C53H92N6O17 (1259518-81-4) → C59H103N7O18 (1259518-83-6)

Guidance literature:

Multi-step reaction with 2 steps

1: water; potassium hydroxide / methanol; dichloromethane / Reflux

2: (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C

With (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; water; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; potassium hydroxide; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jal086112

Reference yield:

C14H22O7S2 (1292296-26-4) → C59H103N7O18 (1259518-83-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sodium azide / N,N-dimethyl-formamide / 18 h / 50 °C

1.2: 20 - 50 °C

2.1: sodium hydroxide / water / 0 - 20 °C / pH 10

3.1: hydrogen; palladium(II) hydroxide / methanol / 4.5 h / 20 °C / Inert atmosphere

4.1: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

5.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 80 °C

6.1: water; potassium hydroxide / methanol; dichloromethane / Reflux

7.1: (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C

With sodium azide; (benzotriazole-1-yloxy)tris(pyrrolidino)phosphonium hexafluorophosphate; carbon tetrabromide; water; hydrogen; palladium(II) hydroxide; potassium carbonate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; triphenylphosphine; potassium hydroxide; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1021/jal086112

upstream raw materials:

C₁₄H₂₂O₇S₂

C₅₃H₉₂N₆O₁₇

C₅₂H₉₀N₆O₁₇

methyl 6-aminocaproate hydrochloride

Downstream raw materials:

C₅₈H₁₀₁N₇O₁₈