1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

Base Information

Chemical Name:1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid
CAS No.:1166831-75-9
Molecular Formula:C₁₂H₁₂FN₃O₃
Molecular Weight:265.244
Hs Code.:

Synonyms:1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

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Chemical Property of 1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

Chemical Property:

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Technology Process of 1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

There total 1 articles about 1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₃H₁₄FN₃O₃

: 1166831-75-9
1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

Guidance literature:: C₁₃H₁₄FN₃O₃; With sodium hydroxide; water; In ethanol; at 20 ℃; for 1h;

With hydrogenchloride; In water; at 0 ℃; pH=4;

Reference yield:

: 1166831-75-9
1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

: 75907-83-4,1422554-22-0
2-fluoro-N'-hydroxybenzenecarboximidamide

: 1166829-03-3
3-(2-fluorophenyl)-5-[1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazole

Guidance literature:: 1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid; 2-fluoro-N'-hydroxybenzenecarboximidamide; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 20 ℃; for 18h;

With pyridine; In acetonitrile; at 150 ℃; for 0.25h; Microwave irradiation;

Reference yield:

: 1166831-75-9
1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid

: 1594-58-7
nicotinamide oxime

: 1166828-98-3
3-{5-[1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazol-4-yl]-1,2,4-oxadiazol-3-yl}pyridine

Guidance literature:: 1-(2-fluorophenyl)-5-(2-methoxyethyl)-1H-1,2,3-triazole-4-carboxylic acid; nicotinamide oxime; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In acetonitrile; at 20 ℃; for 18h;

With pyridine; In acetonitrile; at 150 ℃; for 0.333333h; Microwave irradiation;