(Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

Base Information

• Chemical Name: (Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester
• CAS No.: 497181-69-8
• Molecular Formula: C₁₆H₂₁O₅P
• Molecular Weight: 324.313

Synonyms:(Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

Chemical Property of (Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

There total 3 articles about (Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-hydroxy-2-methylidene-3-phenylpropionate (18020-59-2) → (Z)-2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester (497181-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / toluene

2: 3 h / 90 °C

With triethylamine; In toluene;

DOI:10.1055/s-2002-34899

Reference yield:

2-chloro-5,5-dimethyl-[1,3,2]dioxaphosphinane (2428-06-0) → (Z)-2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester (497181-69-8)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / toluene

2: 3 h / 90 °C

With triethylamine; In toluene;

DOI:10.1055/s-2002-34899

Reference yield:

2-[(5,5-dimethyl-[1,3,2]dioxaphosphinan-2-yloxy)-phenyl-methyl]-acrylic acid methyl ester (497181-68-7) → (Z)-2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester (497181-69-8) + (E)-2-(5,5-Dimethyl-2-oxo-2λ5-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

Guidance literature:

at 90 ℃; for 3h;

DOI:10.1055/s-2002-34899

upstream raw materials:

2-[(5,5-dimethyl-[1,3,2]dioxaphosphinan-2-yloxy)-phenyl-methyl]-acrylic acid methyl ester

methyl 3-hydroxy-2-methylidene-3-phenylpropionate

2-chloro-5,5-dimethyl-[1,3,2]dioxaphosphinane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 497181-69-8 (Z)-2-(5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-ylmethyl)-3-phenyl-acrylic acid methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send