N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide

Base Information

• Chemical Name: N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide
• CAS No.: 1416442-80-2
• Molecular Formula: C₃₃H₄₃N₅O₃S
• Molecular Weight: 589.802

Synonyms:N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide

Chemical Property of N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide

Chemical Property:

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Technology Process of N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide

There total 1 articles about N_δ-Boc-N_α-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

Nδ-Boc-Nα-[(2R)-3-phenyl-1-(Fmoc)amino-propan-2-yl]ornithine benzyl amide (1416442-06-2) + C26H38N4O3 (1416442-88-0) + phenyl isothiocyanate (103-72-0) → Nδ-Boc-Nα-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide (1416442-80-2)

Guidance literature:

N_δ-Boc-N_α-[(2R)-3-phenyl-1-(Fmoc)amino-propan-2-yl]ornithine benzyl amide; With diethylamine; at 20 ℃; for 2h;

C₂₆H₃₈N₄O₃; phenyl isothiocyanate; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1016/j.ejmech.2012.10.015

Reference yield: 100.0%

Nδ-Boc-Nα-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide (1416442-80-2) → Nα-[(2R)-3-phenyl-1-(3-phenylthioureido)propan-2-yl]ornithine benzyl amide dihydrochloride

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 2h;

DOI:10.1016/j.ejmech.2012.10.015

upstream raw materials:

N_δ-Boc-N_α-[(2R)-3-phenyl-1-(Fmoc)amino-propan-2-yl]ornithine benzyl amide

C₂₆H₃₈N₄O₃

phenyl isothiocyanate

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