(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

Base Information

Chemical Name:(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride
CAS No.:1313219-21-4
Molecular Formula:C₁₇H₁₇BrN₂O*ClH
Molecular Weight:381.7
Hs Code.:

Synonyms:(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

Suppliers and Price of (S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

There total 1 articles about (S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 574744-39-1,911373-69-8
(1S)-[1-(4-methoxyphenyl)ethyl]amine hydrochloride

: 773837-37-9
sodium cyanide

: 6630-33-7
ortho-bromobenzaldehyde

: 1313219-21-4
(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

Guidance literature:: In methanol; water; at 20 ℃; for 16h;
DOI:10.1021/jo200528s

Reference yield: 80.0%

: 1313219-21-4
(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

: 1313219-33-8
(S)-α-amino-α-(2-bromophenyl)acetic acid hydrochloride

Guidance literature:: With hydrogenchloride; water; at 90 ℃;
DOI:10.1021/jo200528s

Reference yield:

: 1313219-21-4
(S,S)-α-(2-bromophenyl)-α-[1-(4-methoxyphenyl)ethylamino]acetonitrile hydrochloride

: 1176305-56-8
methyl N-Boc-(S)-2-(2-bromophenyl)glycinate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / water / 3.5 h / 90 °C

2: thionyl chloride / 28 h / 0 - 20 °C

3: triethylamine / tetrahydrofuran / 3 h / 20 °C

With hydrogenchloride; thionyl chloride; triethylamine; In tetrahydrofuran; water;