N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide

Base Information

Chemical Name:N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide
CAS No.:1166-34-3
Molecular Formula:C20H24 N2 O S
Molecular Weight:340.489
Hs Code.:2930909090
DSSTox Substance ID:DTXSID7045653
Wikidata:Q27164041
ChEMBL ID:CHEMBL533822
Mol file:1166-34-3.mol

Synonyms:TCMDC-125843;DTXSID7045653;CHEMBL533822;2'-(3-dimethylaminopropylthio) cinnamanilide;Q27164041;N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide

Suppliers and Price of N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Cinanserin
100mg
$ 1115.00

American Custom Chemicals Corporation
2'-(3-DIMETHYLAMINOPROPYLTHIO)CINNAMANILIDE 95.00%
10MG
$ 281.40

Alfa Aesar
Cinanserin hydrochloride, 99+%
50mg
$ 539.00

Alfa Aesar
Cinanserin hydrochloride, 99+%
10mg
$ 149.00

Total 10 raw suppliers

Chemical Property of N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide

Chemical Property:

Vapor Pressure:6.76E-11mmHg at 25°C
Melting Point:82-83 °C
Boiling Point:519.5°Cat760mmHg
PKA:13.46±0.70(Predicted)
Flash Point:268°C
PSA：57.64000
Density:1.13g/cm³
LogP:4.45530
Storage Temp.:Desiccate at RT
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:Soluble to 50 mM in water
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:340.16093457
Heavy Atom Count:24
Complexity:391

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cinanserin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCSC1=CC=CC=C1NC(=O)C=CC2=CC=CC=C2
Uses Serotonin inhibitor. A 5-HT antagonist

Technology Process of N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide

There total 6 articles about N-[2-[3-(dimethylamino)propylthio]phenyl]-3-phenyl-2-propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 137-07-5
2-amino-benzenethiol

: 1166-34-3
cinanserin

Guidance literature:: Multi-step reaction with 2 steps

2: (i) NaNH₂, (ii) /BRN= 605294/

DOI:10.1021/jm00341a017

Reference yield:

: 1134-77-6
2-(3-dimethylaminopropylthio)aniline

: 102-92-1,17082-09-6
cinnamoyl chloride

: 1166-34-3
cinanserin

Guidance literature:: In chloroform;
DOI:10.1021/jm00333a039

Reference yield:

: 109-54-6
3-(Dimethylamino)propyl chloride

: 1166-34-3
cinanserin

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NaOMe, iPrOH, (ii) /BRN= 605294/, toluene

2: CHCl₃

In chloroform;
DOI:10.1021/jm00333a039