Thiophene-3,4-dicarbaldehyde

Base Information

• Chemical Name: Thiophene-3,4-dicarbaldehyde
• CAS No.: 1073-31-0
• Molecular Formula: C6H4O2S
• Molecular Weight: 140.163
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID10483946
• Nikkaji Number: J713.433I
• Wikidata: Q82321830
• Mol file: 1073-31-0.mol

Synonyms:thiophene-3,4-dicarbaldehyde;1073-31-0;3,4-Thiophenedicarboxaldehyde;thiophene-3,4-dicarboxaldehyde;SCHEMBL843718;3,4-Thiophene dicarboxaldehyde;DTXSID10483946;GCYSRLXIEWTZNM-UHFFFAOYSA-N;BAA07331;MFCD09033442;AKOS006332078;AS-50362;CS-0378289;T3343;EN300-370717;O12152

Chemical Property of Thiophene-3,4-dicarbaldehyde

Chemical Property:

• Vapor Pressure: 0.002mmHg at 25°C
• Melting Point: 81 °C
• Refractive Index: 1.669
• Boiling Point: 293.888 °C at 760 mmHg
• Flash Point: 131.539 °C
• PSA: 62.38000
• Density: 1.371 g/cm³
• LogP: 1.37310
• Storage Temp.: 2-8°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 139.99320054
• Heavy Atom Count: 9
• Complexity: 110

Purity/Quality:

97% ^*data from raw suppliers

3,4-Thiophenedicarboxaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CS1)C=O)C=O

Technology Process of Thiophene-3,4-dicarbaldehyde

There total 5 articles about Thiophene-3,4-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

[4-(hydroxymethyl)-3-thienyl]methanol (18354-73-9) → 3,4-thiophene dicarboxaldehyde (1073-31-0)

Guidance literature:

With manganese(IV) oxide; In 1,4-dioxane; at 96 ℃; for 0.75h; Inert atmosphere;

DOI:10.1016/j.ejmech.2019.111562

Reference yield: 77.0%

3,4-dibromothiophene (3141-26-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3,4-thiophene dicarboxaldehyde (1073-31-0)

Guidance literature:

3,4-dibromothiophene; With n-butyllithium; Inert atmosphere;

N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.3987/COM-20-14282

Reference yield:

3,4-dicyanothiophene (18853-32-2) → 3,4-thiophene dicarboxaldehyde (1073-31-0)

Guidance literature:

With diisobutylaluminium hydride; In toluene; benzene;

upstream raw materials:

3,4-diiodothiophene

N,N-dimethyl-formamide

3,4-dibromothiophene

3,4-dicyanothiophene

Downstream raw materials:

3,4-Bis-(o-methylstyryl)thiophene

thieno<3,4-d>thiepin

N-(p-tolyl)-5,6-dihydro-4-oxo-4H-thieno<3,4-c>pyrrole

N-(p-tolyl)-4-(p-tolyl)imino-5,6-dihydro-4H-thieno<3,4-c>pyrrole