ALPHA-CHLORO-4-NITROBENZALDOXIME

Base Information

• Chemical Name: ALPHA-CHLORO-4-NITROBENZALDOXIME
• CAS No.: 1011-84-3
• Molecular Formula: C7H5ClN2O3
• Molecular Weight: 200.581
• Hs Code.: 2925290090
• Mol file: 1011-84-3.mol

Synonyms:Benzohydroximoylchloride, p-nitro- (8CI);4-Nitrobenzohydroxamic acid chloride;4-Nitrobenzohydroxamoyl chloride;4-Nitrobenzohydroximoyl chloride;N-Hydroxy-4-nitrobenzenecarboximidoyl chloride;p-Nitrobenzohydroxamoylchloride;p-Nitrobenzohydroximoyl chloride;p-Nitrophenylhydroxamic acidchloride;a-Chloro-4-nitrobenzaldoxime;a-Chloro-p-nitrobenzaldoxime;Benzoyl chloride, p-nitro-, oxime (7CI);4-Nitrobenzenehydroximic acid chloride;

Chemical Property of ALPHA-CHLORO-4-NITROBENZALDOXIME

Chemical Property:

• Vapor Pressure: 2.43E-06mmHg at 25°C
• Melting Point: 66-67 °C
• Refractive Index: 1.612
• Boiling Point: 376.6 °C at 760 mmHg
• PKA: 9.73±0.70(Predicted)
• Flash Point: 181.5 °C
• PSA: 78.41000
• Density: 1.5 g/cm³
• LogP: 2.49260
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

N-Hydroxy-4-nitrobenzimidoylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ALPHA-CHLORO-4-NITROBENZALDOXIME

There total 6 articles about ALPHA-CHLORO-4-NITROBENZALDOXIME which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-nitrobenzaldehyde oxime (1129-37-9,174848-02-3,20707-69-1) → 4-nitrobenzohydroximoyl chloride (1011-84-3)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield: 86.0%

4-nitrobenzaldehyde oxime (1129-37-9,174848-02-3,20707-69-1) → 4-nitrobenzohydroximoyl chloride (1011-84-3)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1039/d0nj03474f

Reference yield:

4-nitrobenzaldehdye (555-16-8) → 4-nitrobenzohydroximoyl chloride (1011-84-3)

Guidance literature:

Multi-step reaction with 2 steps

1: HONH₂ / ethanol / 5 h / 50 °C

2: N-chlorosuccinimide; HCl / dioxane / 1 h / 20 °C

With hydrogenchloride; N-chloro-succinimide; hydroxylamine; In 1,4-dioxane; ethanol;

DOI:10.1016/j.bmcl.2007.04.024

upstream raw materials:

4-nitrobenzaldehyde oxime

4-nitrobenzaldehyde oxime

N-hydroxy-N-(1,1-dimethylethyl)-4-nitrobenzamide

4-nitrobenzaldehdye

Downstream raw materials:

1-[hydroxyimino-(4-nitro-phenyl)-methyl]-piperidine

p-nitro-N-phenylbenzamide oxime

N'-hydroxy-4-nitrobenzimidamide

3,4-di(4-nitrophenyl)-1,2,5-oxadiazole N-oxide