trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

Base Information

• Chemical Name: trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin
• CAS No.: 94111-53-2
• Molecular Formula: C₅₅H₆₀N₆O
• Molecular Weight: 821.121
• Mol file: 94111-53-2.mol

Synonyms:trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

Chemical Property of trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

There total 2 articles about trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

α,α-5,15-bis(2'-aminophenyl)-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-50-9,94160-65-3,138808-62-5) + p-tert-butyl benzoyl chloride (1710-98-1) → trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-53-2) + trans-5,15-bis-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-80-5,94233-44-0)

Guidance literature:

With triethylamine; In dichloromethane; for 2h; Heating;

DOI:10.1021/ja00290a027

Reference yield:

4-(1,1-dimethylethyl)benzoic acid (98-73-7) → trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-53-2)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / CHCl₃ / 3 h / Heating

2: 50 percent / triethylamine / CH₂Cl₂ / 2 h / Heating

With thionyl chloride; triethylamine; In dichloromethane; chloroform;

DOI:10.1021/ja00290a027

Reference yield: 94.0%

methyl 2-(carboxyacetyl)pyridine-6-carboxylate (94111-68-9) + trans-5-(o-aminophenyl)-15--2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-53-2) → trans-5--15-phenyl>-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin (94111-69-0)

Guidance literature:

With dicyclohexyl-carbodiimide; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1021/ja00290a027

upstream raw materials:

α,α-5,15-bis(2'-aminophenyl)-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

p-tert-butyl benzoyl chloride

4-(1,1-dimethylethyl)benzoic acid

Downstream raw materials:

trans-5--15-phenyl>-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

trans-5--15-phenyl>-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin

trans-5--15-phenyl>-2,8,12,18-tetraethyl-3,7,13,17-tetramethylporphyrin