Technology Process of 2-Azaspiro[4.4]nonane
There total 15 articles about 2-Azaspiro[4.4]nonane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium hydroxide - carbon;
In
methanol;
for 16h;
under 1368 Torr;
Ambient temperature;
DOI:10.3987/COM-93-6465
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 54 percent / thionyl chloride
2: 52 percent / triethylamine / benzene / 15.5 h / Heating
3: 26 percent / sodium borohydride / acetonitrile; methanol / 1 h / Irradiation
4: 92 percent / lithium aluminum hydride / diethyl ether / 0.5 h / Ambient temperature
5: 65 percent / H2 / 20percent palladium hydroxide/C / methanol / 16 h / 1368 Torr / Ambient temperature
With
sodium tetrahydroborate; lithium aluminium tetrahydride; thionyl chloride; hydrogen; triethylamine;
palladium hydroxide - carbon;
In
methanol; diethyl ether; acetonitrile; benzene;
DOI:10.3987/COM-93-6465
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 10percent KOH
2: 54 percent / thionyl chloride
3: 52 percent / triethylamine / benzene / 15.5 h / Heating
4: 26 percent / sodium borohydride / acetonitrile; methanol / 1 h / Irradiation
5: 92 percent / lithium aluminum hydride / diethyl ether / 0.5 h / Ambient temperature
6: 65 percent / H2 / 20percent palladium hydroxide/C / methanol / 16 h / 1368 Torr / Ambient temperature
With
potassium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; thionyl chloride; hydrogen; triethylamine;
palladium hydroxide - carbon;
In
methanol; diethyl ether; acetonitrile; benzene;
DOI:10.3987/COM-93-6465
