C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide

Base Information

• Chemical Name: C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide
• CAS No.: 1032273-35-0
• Molecular Formula: C₁₈H₁₆BrF₂N₃O₂S
• Molecular Weight: 456.311
• Mol file: 1032273-35-0.mol

Synonyms:C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide

Chemical Property of C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide

Chemical Property:

Purity/Quality:

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Technology Process of C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide

There total 1 articles about C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

4-bromo-4,4-difluoro-1-phenylbutane-1,3-dione (1032273-54-3) + 4-Hydrazino-N-methylbenzenemethanesulphonamide hydrochloride (88933-16-8) → C-[4-(3-(bromodifluoromethyl)-5-phenylpyrazol-1-yl)-phenyl]-N-methylmethanesulfonamide (1032273-35-0)

Guidance literature:

With sulfuric acid; In N,N-dimethyl-formamide; at 20 - 120 ℃; regioselective reaction;

DOI:10.1016/j.jfluchem.2009.12.017

upstream raw materials:

4-bromo-4,4-difluoro-1-phenylbutane-1,3-dione

4-Hydrazino-N-methylbenzenemethanesulphonamide hydrochloride