tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

Base Information

Chemical Name:tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate
CAS No.:1164100-78-0
Molecular Formula:C₃₂H₃₀N₆O₂S
Molecular Weight:562.695
Hs Code.:

Synonyms:tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

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Chemical Property of tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

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Technology Process of tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

There total 1 articles about tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1164100-77-9
tert-butyl 4-(4-bromo-2,6-dimethylphenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

: 1692-15-5
4-pyridylboronic acid

: 1164100-78-0
tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; water; at 80 ℃; for 10h;

Reference yield:

: 1164100-78-0
tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate

: 1164100-36-0
4-(4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-ylamino)benzonitrile

Guidance literature:: tert-butyl 4-(2,6-dimethyl-4-(pyridin-4-yl)phenylthio)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-yl-4-cyanophenylcarbamate; With trifluoroacetic acid; at 25 ℃; for 2h;

With water; sodium hydrogencarbonate;