16-Methylpregnane-17,21-diol-3,20-dione 21-acetate

Base Information

Chemical Name:16-Methylpregnane-17,21-diol-3,20-dione 21-acetate
CAS No.:28439-55-6
Molecular Formula:C₂₄H₃₆O₅
Molecular Weight:404.547
Hs Code.:
Mol file:28439-55-6.mol

Synonyms:5a-Pregnane-3,20-dione,17,21-dihydroxy-16a-methyl-, 21-acetate (6CI,8CI); 16a-Methyl-17,21-dihydroxy-5a-pregnane-3,20-dione 21-acetate

Suppliers and Price of 16-Methylpregnane-17,21-diol-3,20-dione 21-acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 16-Methylpregnane-17,21-diol-3,20-dione 21-acetate

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 16-Methylpregnane-17,21-diol-3,20-dione 21-acetate

There total 6 articles about 16-Methylpregnane-17,21-diol-3,20-dione 21-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.8%

: 19784-86-2
16α-Methyl-5α-pregnane-3β,17α,21-triol-20-one 21-acetate

: 28439-55-6
16α-Methyl-5α-pregnane-17α,21-diol-3,20-dione 21-acetate

Guidance literature:: With chromium(VI) oxide; sulfuric acid; In dichloromethane; at 20 - 22 ℃; for 2h;
DOI:10.1007/BF00765387

Reference yield:

: 19971-47-2
16α-Methyl-5α-pregnane-3β,17α-diol-20-one

: 28439-55-6
16α-Methyl-5α-pregnane-17α,21-diol-3,20-dione 21-acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 86.7 percent / 10percent methanolic HCl, Br₂ / CH₂Cl₂ / 1 h / 20 - 22 °C

2: 82 percent / triethylamine / acetone / 4 h / Heating

3: 81.8 percent / chromic anhydride, aq. H₂SO₄ / CH₂Cl₂ / 2 h / 20 - 22 °C

With chromium(VI) oxide; hydrogenchloride; sulfuric acid; bromine; triethylamine; In dichloromethane; acetone;
DOI:10.1007/BF00765387

Reference yield:

: 19784-71-5
3β-hydroxy-5α-pregnane-20-one-16α-methyl

: 28439-55-6
16α-Methyl-5α-pregnane-17α,21-diol-3,20-dione 21-acetate

Guidance literature:: Multi-step reaction with 3 steps

1: ueber mehrere Stufen

2: ueber mehrere Stufen

3: CrO₃; aqueous H₂SO₄; acetone

With chromium(VI) oxide; sulfuric acid; acetone;
DOI:10.1021/ja01549a090