Technology Process of N,N-diethyl-o-allyloxymethylbenzamide
There total 3 articles about N,N-diethyl-o-allyloxymethylbenzamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sec-BuLi; N,N,N',N'-tetramethylethylenediamine / tetrahydrofuran; cyclohexane / 0.67 h / -78 °C
1.2: 2.58 g / tetrahydrofuran; cyclohexane / 1 h / -78 - 20 °C
2.1: 1.6 g / NaBH4 / methanol / 0.5 h / 0 - 20 °C
3.1: 94 percent / NaH / tetrahydrofuran / 20 h / 0 - 20 °C
With
sodium tetrahydroborate; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; sodium hydride;
In
tetrahydrofuran; methanol; cyclohexane;
1.1: Metallation / 1.2: Formylation / 2.1: Reduction / 3.1: Etherification;
DOI:10.1016/S0040-4020(99)00338-5
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.6 g / NaBH4 / methanol / 0.5 h / 0 - 20 °C
2: 94 percent / NaH / tetrahydrofuran / 20 h / 0 - 20 °C
With
sodium tetrahydroborate; sodium hydride;
In
tetrahydrofuran; methanol;
1: Reduction / 2: Etherification;
DOI:10.1016/S0040-4020(99)00338-5
