C₁₆H₁₈O₃

Base Information

• Chemical Name: C₁₆H₁₈O₃
• CAS No.: 952060-88-7
• Molecular Formula: C₁₆H₁₈O₃
• Molecular Weight: 258.317
• Mol file: 952060-88-7.mol

Synonyms:C₁₆H₁₈O₃

Chemical Property of C₁₆H₁₈O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₁₈O₃

There total 5 articles about C₁₆H₁₈O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

C16H22O3 (952061-00-6) → C16H18O3 (952060-88-7)

Guidance literature:

With pyridine-SO₃ complex; dimethyl sulfoxide; triethylamine; In dichloromethane;

DOI:10.1016/j.tetlet.2007.07.040

Reference yield:

C15H20O2 (952060-99-0) → C16H18O3 (952060-88-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / K₂CO₃ / methanol

2: 100 percent / K₂OsO₄*2H₂O; NMO / acetone; H₂O

3: 83 percent / SO₃*pyr; DMSO; NEt₃ / CH₂Cl₂

With potassium osmate(VI); N-methyl-2-indolinone; pyridine-SO₃ complex; potassium carbonate; dimethyl sulfoxide; triethylamine; In methanol; dichloromethane; water; acetone;

DOI:10.1016/j.tetlet.2007.07.040

Reference yield:

C17H24O3 (952060-86-5) → C16H18O3 (952060-88-7)

Guidance literature:

Multi-step reaction with 5 steps

1: LiAlH₄ / tetrahydrofuran / -78 - 20 °C

2: Dess-Martin periodinane / CH₂Cl₂ / 0 °C

3: 96 percent / K₂CO₃ / methanol

4: 100 percent / K₂OsO₄*2H₂O; NMO / acetone; H₂O

5: 83 percent / SO₃*pyr; DMSO; NEt₃ / CH₂Cl₂

With potassium osmate(VI); lithium aluminium tetrahydride; N-methyl-2-indolinone; pyridine-SO₃ complex; potassium carbonate; Dess-Martin periodane; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; acetone; 2: Dess-Martin oxidation;

DOI:10.1016/j.tetlet.2007.07.040

upstream raw materials:

C₁₆H₂₂O₃

C₁₇H₂₄O₃

C₁₅H₂₀O₂

C₁₆H₂₀O