trans-p-pentyloxycinnamoyl chloride

Base Information

• Chemical Name: trans-p-pentyloxycinnamoyl chloride
• CAS No.: 77251-78-6
• Molecular Formula: C₁₄H₁₇ClO₂
• Molecular Weight: 252.741
• Mol file: 77251-78-6.mol

Synonyms:trans-p-pentyloxycinnamoyl chloride

Chemical Property of trans-p-pentyloxycinnamoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-p-pentyloxycinnamoyl chloride

There total 13 articles about trans-p-pentyloxycinnamoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-3-(4-Pentyloxy-phenyl)-acrylic acid (108113-57-1) → (E)-3-(4-Pentyloxy-phenyl)-acryloyl chloride (77251-78-6)

Guidance literature:

With thionyl chloride;

DOI:10.1080/10587250307066

Reference yield:

para-coumaric acid (7400-08-0,50940-26-6) → (E)-3-(4-Pentyloxy-phenyl)-acryloyl chloride (77251-78-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / methanol / Reflux

2: thionyl chloride

With thionyl chloride; potassium hydroxide; In methanol;

DOI:10.1080/15421406.2011.591659

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → (E)-3-(4-Pentyloxy-phenyl)-acryloyl chloride (77251-78-6)

Guidance literature:

Multi-step reaction with 3 steps

1: piperidine; pyridine / Heating

2: potassium hydroxide / methanol / Reflux

3: thionyl chloride

With piperidine; pyridine; thionyl chloride; potassium hydroxide; In methanol;

DOI:10.1080/15421406.2011.591659

upstream raw materials:

4-pentyloxy-trans-cinnamic acid

1-Bromopentane

4-hydroxy-benzaldehyde

4-(n-pentyloxy)benzaldehyde

Downstream raw materials:

p-(p'-n-pentyloxycinnamoyloxy) benzaldehyde

(E)-3-(4-Pentyloxy-phenyl)-acrylic acid 4-methoxy-phenyl ester

(E)-3-(4-Pentyloxy-phenyl)-acrylic acid 4-propionyl-phenyl ester

C₂₇H₃₂O₅