Technology Process of C17H18BrNO2
There total 2 articles about C17H18BrNO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1,4-diaza-bicyclo[2.2.2]octane; pyridinium hydrobromide perbromide;
In
dichloromethane;
at 20 ℃;
for 16h;
diastereoselective reaction;
Inert atmosphere;
Molecular sieve;
DOI:10.1021/ol102693e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexanes / 0.75 h / -78 °C / Inert atmosphere
1.2: 3 h / -78 - 20 °C / Inert atmosphere
2.1: 1,4-diaza-bicyclo[2.2.2]octane; pyridinium hydrobromide perbromide / dichloromethane / 16 h / 20 °C / Inert atmosphere; Molecular sieve
With
1,4-diaza-bicyclo[2.2.2]octane; pyridinium hydrobromide perbromide;
In
tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexanes; dichloromethane;
DOI:10.1021/ol102693e
- Guidance literature:
-
With
trimethylaluminum;
In
hexanes; toluene;
at 110 ℃;
for 16h;
Inert atmosphere;
DOI:10.1021/ol102693e