trans-1-Amino-2,3-diphenylaziridine

Base Information

• Chemical Name: trans-1-Amino-2,3-diphenylaziridine
• CAS No.: 28161-60-6
• Molecular Formula: C14H14 N2
• Molecular Weight: 210.279
• DSSTox Substance ID: DTXSID90506102
• Nikkaji Number: J2.180.111I
• Mol file: 28161-60-6.mol

Synonyms:TRANS-1-AMINO-2,3-DIPHENYLAZIRIDINE;28161-60-6;(2S,3S)-2,3-Diphenylaziridin-1-amine;DTXSID90506102

Chemical Property of trans-1-Amino-2,3-diphenylaziridine

Chemical Property:

• PSA: 29.03000
• LogP: 3.29650
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 210.115698455
• Heavy Atom Count: 16
• Complexity: 205

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2C(N2N)C3=CC=CC=C3
• Isomeric SMILES: C1=CC=C(C=C1)[C@H]2[C@@H](N2N)C3=CC=CC=C3

Technology Process of trans-1-Amino-2,3-diphenylaziridine

There total 4 articles about trans-1-Amino-2,3-diphenylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(2RS,3RS)-2,3-diphenylaziridin-1-yl]isoindoline-1,3-dione (29392-97-0,33474-61-2,37079-32-6) → trans-1-amino-2,3-diphenylaziridine (28161-60-6)

Guidance literature:

With hydrazine; In ethanol; at 45 - 48 ℃;

DOI:10.1016/S0040-4039(00)74305-X

Reference yield:

(E)-1,2-diphenyl-ethene (103-30-0) → trans-1-amino-2,3-diphenylaziridine (28161-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Pb(OAc)4 / CH₂Cl₂

2: NH₂NH₂ / ethanol / 45 - 48 °C

With lead(IV) acetate; hydrazine; In ethanol; dichloromethane;

DOI:10.1016/S0040-4039(00)74305-X

Reference yield:

→ trans-2,3-diphenylaziridin-1-amine (28161-59-3,28161-60-6,37079-40-6,78926-46-2)

Guidance literature:

/BRN= 395096/, N2H4*H2O, EtOH;

upstream raw materials:

2-[(2RS,3RS)-2,3-diphenylaziridin-1-yl]isoindoline-1,3-dione

(E)-1,2-diphenyl-ethene

Downstream raw materials:

((2S,3S)-2,3-Diphenyl-aziridin-1-yl)-[1-methyl-3-phenyl-prop-(E)-ylidene]-amine

N-((2S,3S)-2,3-Diphenyl-aziridin-1-yl)-benzamide

((2R,3R)-2,3-Diphenyl-aziridin-1-yl)-carbamic acid 9H-fluoren-9-ylmethyl ester

cis-stilben

Refernces