3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Base Information

• Chemical Name: 3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate
• CAS No.: 1082059-98-0
• Molecular Formula: C₃₂H₃₇NO₇
• Molecular Weight: 547.648
• Mol file: 1082059-98-0.mol

Synonyms:3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Chemical Property of 3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

There total 1 articles about 3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

chemantane (20098-14-0) + C17H17NO4 → 3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate (1082059-98-0)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 25 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.bmcl.2008.07.116

Reference yield:

3-tert-butyl 5-(4-oxo-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate (1082059-98-0) → 3-tert-butyl 5-(cis-4-hydroxy-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate + 3-tert-butyl 5-(trans-4-hydroxy-1-adamantyl) (4S,5R)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-3,5-dicarboxylate

Guidance literature:

With sodium tetrahydroborate; In diethyl ether; at 25 ℃; for 10h;

DOI:10.1016/j.bmcl.2008.07.116

upstream raw materials:

chemantane