N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

Base Information

Chemical Name:N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride
CAS No.:1064708-34-4
Molecular Formula:C₂₂H₂₇NO₃*ClH
Molecular Weight:389.922
Hs Code.:

Synonyms:N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

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Chemical Property of N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

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Technology Process of N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

There total 2 articles about N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.5%

: 1064708-73-1
4-benzoylmethyl-4-piperidinol

: 55214-85-2
1-(1'-bromoethyl)-4-methoxybenzene

: 1064708-34-4
N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

Guidance literature:: 4-benzoylmethyl-4-piperidinol; 1-(1'-bromoethyl)-4-methoxybenzene; With potassium carbonate; potassium iodide; In acetone; for 12h; Reflux;

With hydrogenchloride; In ethanol; pH=2;

Reference yield:

: 1064708-34-4
N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

Guidance literature:

Reference yield: 39.9%

: 1064708-34-4
N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride

: 1064708-70-8
N-(1-(p-methoxyphenyl)ethyl)-4-benzoylmethyl-4-chloropiperidine hydrochloride

Guidance literature:: N-(1-(4-methoxyphenyl)ethyl)-4-benzoylmethyl-4-piperidinol hydrochloride; With thionyl chloride; In dichloromethane; at 20 ℃; for 1h; Cooling with ice;

With potassium carbonate; In dichloromethane; water; for 0.5h;

With hydrogenchloride; In ethanol;