Benzothiazole, 2-ethenyl- (9CI)

Base Information

• Chemical Name: Benzothiazole, 2-ethenyl- (9CI)
• CAS No.: 2544-92-5
• Molecular Formula: C9H7 N S
• Molecular Weight: 161.227
• Hs Code.: 2934999090
• Mol file: 2544-92-5.mol

Synonyms:Benzothiazole,2-vinyl- (6CI,7CI,8CI); 2-Vinylbenzothiazole

Chemical Property of Benzothiazole, 2-ethenyl- (9CI)

Chemical Property:

• PSA: 41.13000
• LogP: 2.93930

Purity/Quality:

99% ^*data from raw suppliers

2-ethenyl-Benzothiazole 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzothiazole, 2-ethenyl- (9CI)

There total 7 articles about Benzothiazole, 2-ethenyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-chlorobenzo[d][1,3]thiazole (615-20-3) + potassium vinyltrifluoroborate → 2-vinyl-1,3-benzothiazole (2544-92-5)

Guidance literature:

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; triethylamine; In isopropyl alcohol; for 16h; Reflux;

DOI:10.1039/c6cc00603e

Reference yield: 81.0%

benzothiazole-2-carbaldehyde (6639-57-2) + methyl-triphenylphosphonium iodide (2065-66-9) → 2-vinyl-1,3-benzothiazole (2544-92-5)

Guidance literature:

methyl-triphenylphosphonium iodide; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.25h; Inert atmosphere;

benzothiazole-2-carbaldehyde; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.orglett.0c01425

Reference yield: 75.0%

2-Methylbenzothiazole (120-75-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → 2-vinyl-1,3-benzothiazole (2544-92-5)

Guidance literature:

With diethyl amine hydrochloride; triethylamine; In 1,4-dioxane; at 100 ℃; for 2h;

DOI:10.1039/c5ra21304e

upstream raw materials:

2-benzothiazol-2-yl-ethanol

2-amino-benzenethiol

2-chloropropionyl chloride

2-methylmercaptobenzothiazole

Downstream raw materials:

5-benzothiazol-2-yl-pentan-2-one

4-(2-Benzothiazolyl)butansaeure