2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI)

Base Information

Chemical Name:2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI)
CAS No.:27981-16-4
Molecular Formula:C₉H₁₄O₃
Molecular Weight:170.208
Hs Code.:
Mol file:27981-16-4.mol

Synonyms:2-Hexenoicacid, 4,5-epoxy-, isopropyl ester (8CI); 2-Propenoic acid,3-(3-methyloxiranyl)-, 1-methylethyl ester (9CI); Isopropyl4,5-epoxy-2-hexenoate

Suppliers and Price of 2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI)

Chemical Property:

Boiling Point:59 - 60 °C (0.5 mmHg)
PSA：38.83000
LogP:1.28150

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI)

There total 7 articles about 2-Propenoicacid,3-(3-methyloxiranyl)-,1-methylethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 67-63-0,8013-70-5
isopropyl alcohol

: 183479-35-8
(E)-(4R,5R)-5-Chloro-4-hydroxy-hex-2-enoic acid methyl ester

: 27981-16-4
isopropyl (4R,5S)-4,5-epoxy-(2E)-hexenoate

Guidance literature:: With sodium hydride; at 0 ℃; for 0.5h;
DOI:10.1016/0957-4166(96)00333-3

Reference yield:

: 51830-12-7
Epoxy-4,5 hexene-2 (E) oate de methyle

: 27981-16-4
isopropyl (4R,5S)-4,5-epoxy-(2E)-hexenoate

Guidance literature:: Multi-step reaction with 7 steps

1: 60 percent / BF₃*Et₂O / CH₂Cl₂ / 1 h / Ambient temperature

2: 90 percent / pyridine

4: 84 percent / MeONa / methanol / 0.5 h / 0 °C

5: 81 percent / N-chlorosuccinimide, Ph₃P / acetonitrile / 3 h / 0 °C

6: 87 percent / (iPr)2NEt / CH₂Cl₂; various solvent(s) / 1 h / -20 °C

7: 89 percent / NaH / 0.5 h / 0 °C

With pyridine; N-chloro-succinimide; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In methanol; dichloromethane; acetonitrile;
DOI:10.1016/0957-4166(96)00333-3

Reference yield:

: 183625-29-8
methyl (4R,5S)-4-benzyloxy-5-hydroxy-2(E)-hexenoate

: 27981-16-4
isopropyl (4R,5S)-4,5-epoxy-(2E)-hexenoate

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / N-chlorosuccinimide, Ph₃P / acetonitrile / 3 h / 0 °C

2: 87 percent / (iPr)2NEt / CH₂Cl₂; various solvent(s) / 1 h / -20 °C

3: 89 percent / NaH / 0.5 h / 0 °C

With N-chloro-succinimide; sodium hydride; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In dichloromethane; acetonitrile;
DOI:10.1016/0957-4166(96)00333-3