(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Base Information

Chemical Name:(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane
CAS No.:915769-84-5
Molecular Formula:C₂₈H₃₄O₄Si
Molecular Weight:462.661
Hs Code.:

Synonyms:(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Suppliers and Price of (2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

There total 2 articles about (2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4,5-bis-benzyloxy-2-ethoxy-2-furan-3-yl-6-methyl-tetrahydro-pyran

: 915769-84-5
(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 0.39 g / NaCNBH₃; HCl / ethanol / 50 °C

2.1: LDA / tetrahydrofuran / 3.5 h / -78 °C

2.2: 70 percent / tetrahydrofuran / 0.08 h / -78 °C

With hydrogenchloride; sodium cyanoborohydride; lithium diisopropyl amide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.tet.2007.04.031

Reference yield:

: (4R,5R,6R)-4,5-Bis-benzyloxy-6-methyl-tetrahydro-pyran-2-one

: 915769-84-5
(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -78 °C

1.2: tetrahydrofuran; hexane / 0.5 h / -78 °C

1.3: HCl / 0.17 h

2.1: 0.39 g / NaCNBH₃; HCl / ethanol / 50 °C

3.1: LDA / tetrahydrofuran / 3.5 h / -78 °C

3.2: 70 percent / tetrahydrofuran / 0.08 h / -78 °C

With hydrogenchloride; n-butyllithium; sodium cyanoborohydride; lithium diisopropyl amide; In tetrahydrofuran; ethanol; hexane;
DOI:10.1016/j.tet.2007.04.031

Reference yield: 94.0%

: 915769-84-5
(2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane

: 915769-82-3
(2R,4R,5R,6R)-2-({3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylsilanyl)ethanol

Guidance literature:: (2R,4R,5R,6R)-{3-[4,5-bis(benzyloxy)-6-methyltetrahydropyran-2-yl]furan-2-yl}dimethylvinylsilane; With 9-borabicyclo[3.3.1]nonane dimer; In tetrahydrofuran; at 20 ℃; for 2h;

With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; at 0 ℃; for 0.25h; Further stages.;
DOI:10.1016/j.tet.2007.04.031