4-(9'-anthryl)-4-iodobiphenyl

Base Information

• Chemical Name: 4-(9'-anthryl)-4-iodobiphenyl
• CAS No.: 668493-39-8
• Molecular Formula: C₂₆H₁₇I
• Molecular Weight: 456.325
• Mol file: 668493-39-8.mol

Synonyms:4-(9'-anthryl)-4-iodobiphenyl

Chemical Property of 4-(9'-anthryl)-4-iodobiphenyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(9'-anthryl)-4-iodobiphenyl

There total 3 articles about 4-(9'-anthryl)-4-iodobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

4,4'-diiodobiphenyl (3001-15-8) + anthracene-9-boronic acid (100622-34-2) → 4,4'-bis(9-anthryl)biphenyl (125011-62-3) + 4-(9'-anthryl)-4-iodobiphenyl (668493-39-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; at 80 ℃;

DOI:10.1021/jo035147y

Reference yield:

biphenyl (92-52-4,1594-86-1) → 4-(9'-anthryl)-4-iodobiphenyl (668493-39-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / periodic acid; sulfuric acid; iodine / acetic acid / CCl₄ / 4 h / 80 °C

2: 50 percent / Pd(PPh₃)4; K₂CO₃ / tetrahydrofuran / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sulfuric acid; iodine; potassium carbonate; periodic acid; acetic acid; In tetrahydrofuran; tetrachloromethane; 2: Suzuki cross-coupling;

DOI:10.1021/jo035147y

Reference yield:

9-Bromoanthracene (1564-64-3) → 4-(9'-anthryl)-4-iodobiphenyl (668493-39-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-BuLi / tetrahydrofuran / 1 h / cooling

1.2: trimethyl borate / tetrahydrofuran / 2 h / cooling

1.3: HCl / tetrahydrofuran; H₂O

2.1: 50 percent / Pd(PPh₃)4; K₂CO₃ / tetrahydrofuran / 80 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; n-butyllithium; potassium carbonate; In tetrahydrofuran; 2.1: Suzuki cross-coupling;

DOI:10.1021/jo035147y

upstream raw materials:

4,4'-diiodobiphenyl

anthracene-9-boronic acid

biphenyl

9-Bromoanthracene