(2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine

Base Information

• Chemical Name: (2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine
• CAS No.: 721926-04-1
• Molecular Formula: C₁₁H₁₄BrN
• Molecular Weight: 242.127
• Mol file: 721926-04-1.mol

Synonyms:(2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine

Chemical Property of (2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine

There total 1 articles about (2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(S)-1-phenyl-ethylamine (2627-86-3) + 2-bromo-1,1-dideuteroprop-2-en-1-ol (181712-58-3) → (2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine (721926-04-1)

Guidance literature:

2-bromo-1,1-dideuteroprop-2-en-1-ol; With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at -30 - 0 ℃; for 1.5h;

(S)-1-phenyl-ethylamine; In tetrahydrofuran; for 18h; Heating;

DOI:10.1021/ja0482684

Reference yield: 91.0%

(2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine (721926-04-1) → (S)-N-(1-phenylethyl)-2-methylideneaziridine (178313-97-8)

Guidance literature:

With sodium amide; In diethyl ether; ammonia; at -78 ℃; for 1h;

DOI:10.1021/ja0482684

Reference yield: 85.0%

(2-bromo-1,1-dideuteroprop-2-enyl)-[(S)-1-phenylethyl]amine (721926-04-1) → 3,3-dideutero-2-methylene-1-[(S)-1-phenylethyl]aziridine

Guidance literature:

With sodium amide; In diethyl ether; ammonia; for 0.0833333h;

DOI:10.1021/ja0482684

upstream raw materials:

(S)-1-phenyl-ethylamine

2-bromo-1,1-dideuteroprop-2-en-1-ol

Downstream raw materials:

(S)-N-(1-phenylethyl)-2-methylideneaziridine