Technology Process of (3R,6S)-6-para-methoxybenzyloxyhept-1-en-3-ol
There total 8 articles about (3R,6S)-6-para-methoxybenzyloxyhept-1-en-3-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
trimethylsulphonium iodide;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -20 ℃;
for 0.75h;
C14H20O3;
In
tetrahydrofuran; hexane;
at -20 - 20 ℃;
for 4.5h;
Further stages.;
DOI:10.1016/j.tetasy.2008.03.024
- Guidance literature:
-
With
immobilized preparation of lipase from Candida antarctica B on acrylic resin;
In
di-isopropyl ether;
at 25 ℃;
for 6h;
Enzymatic reaction;
DOI:10.1021/jo5012575
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: lithium aluminium tetrahydride / diethyl ether / 2 h / 0 °C
2.1: immobilized preparation of lipase from Candida antarctica B on acrylic resin / hexane / 0.83 h / 25 °C / Enzymatic reaction
3.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h / -5 °C
3.2: 4 h / -5 °C
4.1: 4-methylmorpholine N-oxide; osmium(VIII) oxide / acetone; water; tert-butyl alcohol / 24 h / 25 °C
5.1: sodium periodate / water; acetonitrile / 2 h / 10 °C
6.1: tetrahydrofuran / 3 h / -78 °C
7.1: immobilized preparation of lipase from Candida antarctica B on acrylic resin / di-isopropyl ether / 6 h / 25 °C / Enzymatic reaction
With
sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; sodium hydride; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; diethyl ether; hexane; di-isopropyl ether; water; N,N-dimethyl-formamide; acetone; acetonitrile; mineral oil; tert-butyl alcohol;
DOI:10.1021/jo5012575
