1,3-Benzodioxole-2-methanol

Base Information

Chemical Name:1,3-Benzodioxole-2-methanol
CAS No.:22946-12-9
Molecular Formula:C8H8 O3
Molecular Weight:152.15
Hs Code.:2932999099
DSSTox Substance ID:DTXSID70606199
Wikidata:Q82504837
Mol file:22946-12-9.mol

Synonyms:22946-12-9;1,3-Benzodioxole-2-methanol;SCHEMBL4333283;DTXSID70606199;NVFNURDSPUTUOR-UHFFFAOYSA-N;benzo[d][1,3]dioxol-2-ylmethanol;(2H-1,3-Benzodioxol-2-yl)methanol;DB-259162

Suppliers and Price of 1,3-Benzodioxole-2-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1,3-Benzodioxole-2-methanol

Chemical Property:

PSA：38.69000
LogP:0.77620
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:152.047344113
Heavy Atom Count:11
Complexity:123

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)OC(O2)CO

Technology Process of 1,3-Benzodioxole-2-methanol

There total 2 articles about 1,3-Benzodioxole-2-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 57984-85-7
methyl benzo[1,3]dioxole-2-carboxylate

: 22946-12-9
benzo[1,3]dioxol-2-ylmethanol

Guidance literature:: methyl benzo[1,3]dioxole-2-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 1h;

With sodium hydrogencarbonate; In tetrahydrofuran; methanol; water; at 0 - 20 ℃; for 0.5h;

Reference yield:

: 120-80-9,19481-10-8,37349-32-9
benzene-1,2-diol

: 22946-12-9
benzo[1,3]dioxol-2-ylmethanol

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol / Heating

2: 0.75 g / LiAlH₄ / tetrahydrofuran / 1 h

With lithium aluminium tetrahydride; sodium methylate; In tetrahydrofuran; methanol;
DOI:10.1021/jm040124c