(4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine

Base Information

• Chemical Name: (4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine
• CAS No.: 124600-99-3
• Molecular Formula: C₂₈H₂₆BBrN₂O₄S₂
• Molecular Weight: 609.372
• Mol file: 124600-99-3.mol

Synonyms:(4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine

Chemical Property of (4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine

There total 5 articles about (4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-N-((1R,2R)-2-{[(4-methylphenyl)sulfonyl]amino}-1,2-diphenylethyl)benzenesulfonamide (121758-19-8) → (4R,5R)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine (124600-99-3,121758-17-6)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 ℃; for 1h;

DOI:10.1002/anie.200390322

Reference yield:

(1S,2S)-N,N'-bis((4-methylphenyl)sulfonyl)-1,2-diphenylethane-1,2-diamine (170709-41-8) → (4S,5S)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine (124600-99-3)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/ol006674w

Reference yield:

boron tribromide (10294-33-4) + 4-methyl-N-((1R,2R)-2-{[(4-methylphenyl)sulfonyl]amino}-1,2-diphenylethyl)benzenesulfonamide (121758-19-8) → (4R,5R)-2-bromo-1,3-bis[(4-methylphenyl)sulfonyl]-4,5-diphenyl-1,3,2-diazaborolidine (124600-99-3,121758-17-6)

Guidance literature:

In dichloromethane; react. of bis-sulfonamide with BBr3 in CH2Cl2 for 1 h at 23°C;

DOI:10.1021/ja00196a081

upstream raw materials:

4-methyl-N-((1R,2R)-2-{[(4-methylphenyl)sulfonyl]amino}-1,2-diphenylethyl)benzenesulfonamide

boron tribromide

(1S,2S)-N,N'-bis((4-methylphenyl)sulfonyl)-1,2-diphenylethane-1,2-diamine

Downstream raw materials:

(R)-1-phenyl-3-butyn-1-ol

(R)-1-phenyl-2,3-butanedien-1-ol

(R)-5,5-dimethyl-1,2-hexadien-4-ol

1-phenylhex-1-en-5-yn-3-ol