trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

Base Information

Chemical Name:trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane
CAS No.:130944-30-8
Molecular Formula:C₂₃H₂₆FNO₃
Molecular Weight:383.463
Hs Code.:

Synonyms:trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

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Chemical Property of trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

Chemical Property:

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Technology Process of trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

There total 3 articles about trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 130944-28-4
trans-1-<4-(4-fluorobenzoyl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

: 130944-30-8
trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

Guidance literature:: With potassium borohydride; In methanol; at 30 ℃; for 18h;

Reference yield:

: 56346-57-7
(4-fluorophenyl)-piperidin-4-ylmethanone

: 130944-30-8
trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 57.7 percent / Et₃N / benzene / 5 h / Heating

2: 76 percent / KBH₄ / methanol / 18 h / 30 °C

With potassium borohydride; triethylamine; In methanol; benzene;

Reference yield:

: 102617-03-8
trans-2-phenoxymethylcyclopropane-1-carbonyl chloride

: 130944-30-8
trans-1-<4-(4-fluorobenzhydryl)piperidin-1-ylcarbonyl>-2-phenoxymethylcyclopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 57.7 percent / Et₃N / benzene / 5 h / Heating

2: 76 percent / KBH₄ / methanol / 18 h / 30 °C

With potassium borohydride; triethylamine; In methanol; benzene;