17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone

Base Information

• Chemical Name: 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone
• CAS No.: 89396-38-3
• Molecular Formula: C₂₈H₄₀N₂O₄S
• Molecular Weight: 500.703
• Mol file: 89396-38-3.mol

Synonyms:17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone

Chemical Property of 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone

There total 2 articles about 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

stanolone acetate (1164-91-6) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone (89396-38-3)

Guidance literature:

With acetic acid; In ethanol; at 25 ℃; for 4h; or reflux, 5 min;

DOI:10.1021/jo00199a006

Reference yield:

17β-acetoxy-5α-androstan-3-one (ethoxycarbonyl)hydrazone (92720-27-9) → 17β-acetoxy-5α-androstan-3-one (p-tolylsulfonyl)hydrazone (89396-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 14 percent / SOCl₂ / CH₂Cl₂ / 1.17 h / -20 °C

2: 92 percent / glacial acetic acid / ethanol / 4 h / 25 °C / or reflux, 5 min

With thionyl chloride; acetic acid; In ethanol; dichloromethane;

DOI:10.1021/jo00199a006

upstream raw materials:

stanolone acetate

toluene-4-sulfonic acid hydrazide

17β-acetoxy-5α-androstan-3-one (ethoxycarbonyl)hydrazone

Refernces