2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Base Information

Chemical Name:2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline
CAS No.:135615-51-9
Molecular Formula:C₃₁H₄₁NO₃
Molecular Weight:475.671
Hs Code.:

Synonyms:2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Suppliers and Price of 2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

There total 7 articles about 2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 135615-50-8
2-<18'-(17'-(Benzyloxy)-14'-hydroxy-19'-methoxysordaric-1'-enyl)>-4,4-dimethyloxazoline

: 135615-51-9
2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Guidance literature:: With hydrogen bromide; In dichloromethane; at 0 ℃; for 1.25h;
DOI:10.1021/jo00019a051

Reference yield:

: 133372-88-0
C₂₆H₃₄O₄

: 135615-51-9
2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Guidance literature:: Multi-step reaction with 7 steps

1: KH / 5 h / 150 - 160 °C

2: thionyl chloride

4: thionyl chloride / benzene / 1.5 h

5: 1.) n-butyllithium / 1.) ether, hexane, 0 deg C, 80 min, 2.) -45 deg C, 0.25 h, then r.t., 0.75 h

6: 1.) ether, hexane, 0 deg C, 80 min, then r.t., 40 min, 2.) ether, r.t., 1 h

7: 127.5 mg / HBr / CH₂Cl₂ / 1.25 h / 0 °C

With n-butyllithium; thionyl chloride; hydrogen bromide; potassium hydride; In dichloromethane; benzene;
DOI:10.1021/jo00019a051

Reference yield:

: 135615-59-7
C₂₅H₃₂O₄

: 135615-51-9
2-<18'-(17'-(Benzyloxy)-2',19'-epoxysordaric-1'(14')-enyl)>-4,4-dimethyloxazoline

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride

3: thionyl chloride / benzene / 1.5 h

4: 1.) n-butyllithium / 1.) ether, hexane, 0 deg C, 80 min, 2.) -45 deg C, 0.25 h, then r.t., 0.75 h

5: 1.) ether, hexane, 0 deg C, 80 min, then r.t., 40 min, 2.) ether, r.t., 1 h

6: 127.5 mg / HBr / CH₂Cl₂ / 1.25 h / 0 °C

With n-butyllithium; thionyl chloride; hydrogen bromide; In dichloromethane; benzene;
DOI:10.1021/jo00019a051