3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

Base Information

Chemical Name:3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine
CAS No.:499157-49-2
Molecular Formula:C₂₈H₃₃FN₂O₂
Molecular Weight:448.581
Hs Code.:

Synonyms:3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

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Chemical Property of 3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

Chemical Property:

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Technology Process of 3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

There total 3 articles about 3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 499157-48-1
3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propylazide

: 499157-49-2
3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

Guidance literature:: With water; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 48h;

Reference yield:

: 3-(2-((3-methyl-1-phenylbutyl)carbamoyl)-4-phenoxymethylphenyl)propanol

: 499157-49-2
3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; methanesulfonyl chloride / dichloromethane / 48 h / 50 °C

2: sodium azide / DMF (N,N-dimethyl-formamide) / 80 °C

3: water; triphenylphosphine / tetrahydrofuran / 48 h / 20 °C

With pyridine; sodium azide; water; methanesulfonyl chloride; triphenylphosphine; In tetrahydrofuran; DMF (N,N-dimethyl-formamide); dichloromethane;

Reference yield:

: C₂₉H₃₅NO₅S

: 499157-49-2
3-[4-phenoxymethyl-2-[1-(4-fluorophenyl)-3-methylbutylaminocarbonyl]phenyl]propanamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / DMF (N,N-dimethyl-formamide) / 80 °C

2: water; triphenylphosphine / tetrahydrofuran / 48 h / 20 °C

With sodium azide; water; triphenylphosphine; In tetrahydrofuran; DMF (N,N-dimethyl-formamide);