3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

Base Information

Chemical Name:3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride
CAS No.:1042055-92-4
Molecular Formula:C₇H₆ClNO₃*ClH
Molecular Weight:224.043
Hs Code.:

Synonyms:3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

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Technology Process of 3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

There total 2 articles about 3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67175-26-2
3-chloro-4-hydroxy-5-nitro-benzoic acid

: 1042055-92-4
3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

Guidance literature:: With hydrogenchloride; 10% palladium on activated carbon; hydrogen; In methanol; water; for 0.5h; under 1551.49 Torr;
DOI:10.1021/jm900012a

Reference yield:

: 3964-58-7
3-chloro-4-hydroxybenzoic acid

: 1042055-92-4
3-amino-5-chloro-4-hydroxybenzoic acid hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid / 2 h / 0 - 20 °C

2: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol; water / 0.5 h / 1551.49 Torr

With hydrogenchloride; hydrogen; nitric acid; palladium 10% on activated carbon; In methanol; water;