C₅₂H₇₀O₁₃S

Base Information

Chemical Name:C₅₂H₇₀O₁₃S
CAS No.:457064-18-5
Molecular Formula:C₅₂H₇₀O₁₃S
Molecular Weight:935.186
Hs Code.:

C<sub>52</sub>H<sub>70</sub>O<sub>13</sub>S

Synonyms:C₅₂H₇₀O₁₃S

Suppliers and Price of C₅₂H₇₀O₁₃S

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₅₂H₇₀O₁₃S

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₅₂H₇₀O₁₃S

There total 29 articles about C₅₂H₇₀O₁₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₅₂H₇₀O₁₁S

: 457064-18-5
C₅₂H₇₀O₁₃S

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃;
DOI:10.1021/ol026306n

Reference yield:

: 457064-30-1
(Z)-6-((2R,4aR,6S,7R,9R,9aS)-9-Benzyloxy-7-hydroxy-2-phenyl-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl)-hex-4-enoic acid

: 457064-18-5
C₅₂H₇₀O₁₃S

Guidance literature:: Multi-step reaction with 28 steps

1.1: 2,4,6-Cl₃C₆H₂COCl; Et₃N / tetrahydrofuran / 20 °C

1.2: 71 percent / DMAP / benzene / 80 °C

2.1: 6.39 g / potassium hexamethyldisilazide; hexamethylphosphoric triamide / tetrahydrofuran; toluene / 0.67 h / -78 °C

3.1: 76 percent / triethylamine / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide / 15 h / 50 °C

4.1: AD mix-α; methanesulfonamide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 48 h / 20 °C

5.1: 79 percent / 10-camphorsulfonic acid / CH₂Cl₂ / 1 h / 20 °C

6.1: DIBALH / CH₂Cl₂; toluene / 0.5 h / -78 °C

7.1: 2,6-lutidine / CH₂Cl₂ / 0 - 20 °C

8.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / -20 °C

9.1: 75 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.33 h / 0 °C

10.1: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C

11.1: 98 percent / potassium tert-butoxide / tetrahydrofuran / 0.42 h / 20 °C

12.1: ethanethiol; zinc triflate / CH₂Cl₂ / 26 h / 20 °C

13.1: 78 percent / CH₂Cl₂ / 0.33 h / 20 °C

14.1: 86 percent / ethanethiol; zinc triflate / CH₂Cl₂ / 1.83 h / 20 °C

15.1: 2,6-lutidine / CH₂Cl₂ / 0.5 h / 20 °C

16.1: 96 percent / camphorsulfonic acid / methanol; CH₂Cl₂ / 0.75 h / 0 °C

17.1: iodine; triphenylphosphine; imidazole / tetrahydrofuran / 1 h / 20 °C

18.1: 86 percent / potassium tert-butoxide / tetrahydrofuran / 17 h / 0 °C

19.1: tetrahydrofuran / 2 h / 20 °C

20.1: 88 percent / sodium hydrogen carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide; H₂O / 17 h / 20 °C

21.1: dimethyldioxirane / CH₂Cl₂ / 0.33 h / -20 °C

22.1: 82 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.25 h / -20 °C

23.1: 79.6 mg / camphorsulfonic acid / CH₂Cl₂ / 0.17 h / 20 °C

24.1: 94 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

25.1: 96 percent / 4-methylmorpholine N-oxide / tetrapropylammonium perruthenate / CH₂Cl₂ / 0.67 h / 20 °C

26.1: zinc triflate / CH₂Cl₂ / 18 h / 20 °C

27.1: CH₂Cl₂ / 20 °C

28.1: m-chloroperbenzoic acid; sodium hydrogen carbonate / CH₂Cl₂ / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; AD-mix-α; borane-THF; methanesulfonamide; 2,4,6-trichlorobenzoyl chloride; camphor-10-sulfonic acid; (1S)-10-camphorsulfonic acid; potassium tert-butylate; tetrabutyl ammonium fluoride; iodine; 3,3-dimethyldioxirane; potassium hexamethylsilazane; zinc trifluoromethanesulfonate; diisobutylaluminium hydride; sodium hydrogencarbonate; 4-methylmorpholine N-oxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; ethanethiol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrapropylammonium perruthennate; camphor-10-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol; 20.1: Suzuki-Miyaura coupling;
DOI:10.1021/ol026306n

Reference yield:

: 457064-29-8
(Z)-6-((2R,4aR,6S,7R,9R,9aS)-9-Benzyloxy-2-phenyl-7-triethylsilanyloxy-hexahydro-1,3,5-trioxa-benzocyclohepten-6-yl)-hex-4-enoic acid ethyl ester

: 457064-18-5
C₅₂H₇₀O₁₃S

Guidance literature:: Multi-step reaction with 29 steps

1.1: Ba(OH)2*8H₂O / dioxane; H₂O / 60 °C

1.2: 88 percent / CSA / CH₂Cl₂; methanol / 20 °C

2.1: 2,4,6-Cl₃C₆H₂COCl; Et₃N / tetrahydrofuran / 20 °C

2.2: 71 percent / DMAP / benzene / 80 °C

3.1: 6.39 g / potassium hexamethyldisilazide; hexamethylphosphoric triamide / tetrahydrofuran; toluene / 0.67 h / -78 °C

4.1: 76 percent / triethylamine / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide / 15 h / 50 °C

5.1: AD mix-α; methanesulfonamide / 2-methyl-propan-2-ol; tetrahydrofuran; H2O / 48 h / 20 °C

6.1: 79 percent / 10-camphorsulfonic acid / CH₂Cl₂ / 1 h / 20 °C

7.1: DIBALH / CH₂Cl₂; toluene / 0.5 h / -78 °C

8.1: 2,6-lutidine / CH₂Cl₂ / 0 - 20 °C

9.1: dimethyldioxirane / CH₂Cl₂; acetone / 1 h / -20 °C

10.1: 75 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.33 h / 0 °C

11.1: 97 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.25 h / 20 °C

12.1: 98 percent / potassium tert-butoxide / tetrahydrofuran / 0.42 h / 20 °C

13.1: ethanethiol; zinc triflate / CH₂Cl₂ / 26 h / 20 °C

14.1: 78 percent / CH₂Cl₂ / 0.33 h / 20 °C

15.1: 86 percent / ethanethiol; zinc triflate / CH₂Cl₂ / 1.83 h / 20 °C

16.1: 2,6-lutidine / CH₂Cl₂ / 0.5 h / 20 °C

17.1: 96 percent / camphorsulfonic acid / methanol; CH₂Cl₂ / 0.75 h / 0 °C

18.1: iodine; triphenylphosphine; imidazole / tetrahydrofuran / 1 h / 20 °C

19.1: 86 percent / potassium tert-butoxide / tetrahydrofuran / 17 h / 0 °C

20.1: tetrahydrofuran / 2 h / 20 °C

21.1: 88 percent / sodium hydrogen carbonate / tetrakis(triphenylphosphine)palladium⁽⁰⁾ / dimethylformamide; H₂O / 17 h / 20 °C

22.1: dimethyldioxirane / CH₂Cl₂ / 0.33 h / -20 °C

23.1: 82 percent / triethylsilane; BH₃*THF / CH₂Cl₂; tetrahydrofuran / 0.25 h / -20 °C

24.1: 79.6 mg / camphorsulfonic acid / CH₂Cl₂ / 0.17 h / 20 °C

25.1: 94 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / 20 °C

26.1: 96 percent / 4-methylmorpholine N-oxide / tetrapropylammonium perruthenate / CH₂Cl₂ / 0.67 h / 20 °C

27.1: zinc triflate / CH₂Cl₂ / 18 h / 20 °C

28.1: CH₂Cl₂ / 20 °C

29.1: m-chloroperbenzoic acid; sodium hydrogen carbonate / CH₂Cl₂ / 0 °C

With 1H-imidazole; 2,6-dimethylpyridine; triethylsilane; N,N,N,N,N,N-hexamethylphosphoric triamide; barium dihydroxide; AD-mix-α; borane-THF; methanesulfonamide; 2,4,6-trichlorobenzoyl chloride; camphor-10-sulfonic acid; (1S)-10-camphorsulfonic acid; potassium tert-butylate; tetrabutyl ammonium fluoride; iodine; 3,3-dimethyldioxirane; potassium hexamethylsilazane; zinc trifluoromethanesulfonate; diisobutylaluminium hydride; sodium hydrogencarbonate; 4-methylmorpholine N-oxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; ethanethiol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrapropylammonium perruthennate; camphor-10-sulfonic acid; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; toluene; tert-butyl alcohol; 21.1: Suzuki-Miyaura coupling;
DOI:10.1021/ol026306n