2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

Base Information

Chemical Name:2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine
CAS No.:78961-53-2
Molecular Formula:C₂₂H₂₄N₂O
Molecular Weight:332.445
Hs Code.:

Synonyms:2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

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Chemical Property of 2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

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Technology Process of 2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

There total 3 articles about 2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.9%

: 78961-51-0
4-<(3'-Indolyl)benzyl>-3-hydroxyquinuclidine

: 78961-53-2
2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 2h; Heating;
DOI:10.1007/BF00765591

Reference yield:

: 24123-89-5
(Z)-2-benzylidene-1-azabicyclo[2.2.2]octan-3-one

: 78961-53-2
2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: 64.8 percent / glacial acetic acid / 14 h / 120 °C

2: 64.9 percent / NaBH₄ / ethanol / 2 h / Heating

With sodium tetrahydroborate; acetic acid; In ethanol;
DOI:10.1007/BF00765591

Reference yield:

: 120-72-9
indole

: 78961-53-2
2-<(3'-Indolyl)-benzyl>-3-hydroxyquinuclidine

Guidance literature:: Multi-step reaction with 2 steps

1: 64.8 percent / glacial acetic acid / 14 h / 120 °C

2: 64.9 percent / NaBH₄ / ethanol / 2 h / Heating

With sodium tetrahydroborate; acetic acid; In ethanol;
DOI:10.1007/BF00765591