(6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal

Base Information

• Chemical Name: (6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal
• CAS No.: 107554-05-2
• Molecular Formula: C₃₀H₄₄O₂
• Molecular Weight: 436.678
• Mol file: 107554-05-2.mol

Synonyms:(6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal

Chemical Property of (6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal

There total 22 articles about (6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

((3E,7E,11E)-4,8,16-Trimethyl-12-vinyloxymethyl-heptadeca-3,7,11,15-tetraenyloxymethyl)-benzene (107554-04-1) → (6E,10E)-13-Benzyloxy-6,10-dimethyl-3-(5-methyl-1-methylene-hex-4-enyl)-trideca-6,10-dienal (107554-05-2)

Guidance literature:

In neat (no solvent); at 190 ℃;

DOI:10.1016/S0040-4039(00)84474-3

Reference yield: 70.0%

((3E,7E,11E)-4,8,16-Trimethyl-12-vinyloxymethyl-heptadeca-3,7,11,15-tetraenyloxymethyl)-benzene (107554-04-1) → (5E,9E)-12-Benzyloxy-5,9-dimethyl-2-(5-methyl-1-methylene-hex-4-enyl)-dodeca-5,9-dienal (107554-05-2)

Guidance literature:

at 190 ℃; for 0.333333h;

DOI:10.1021/jo00242a018

Reference yield:

1-bromo-4-methylpent-3-ene (2270-59-9) → (5E,9E)-12-Benzyloxy-5,9-dimethyl-2-(5-methyl-1-methylene-hex-4-enyl)-dodeca-5,9-dienal (107554-05-2)

Guidance literature:

Multi-step reaction with 5 steps

1: 42 percent / t-BuOK / dimethylformamide / 1 h / Ambient temperature

2: 1.) sodium hydride / 1.) DME, 80 deg C, 1 h, 2.) DME, 80 deg C, 15 min

3: 74 percent / LiAlH₄ / diethyl ether / 2 h / Ambient temperature

4: 78 percent / mercuric acetate, sodium acetate / Ambient temperature

5: 70 percent / 0.33 h / 190 °C

With lithium aluminium tetrahydride; potassium tert-butylate; mercury(II) diacetate; sodium acetate; sodium hydride; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1021/jo00242a018

upstream raw materials:

((3E,7E,11E)-4,8,16-Trimethyl-12-vinyloxymethyl-heptadeca-3,7,11,15-tetraenyloxymethyl)-benzene

1-bromo-4-methylpent-3-ene

3-benzyloxypropan-1-ol

3-(benzyloxy)-1-bromo-2-methyl-2(E)-hexene

Downstream raw materials:

2-[(5E,9E)-12-Benzyloxy-5,9-dimethyl-2-(5-methyl-1-methylene-hex-4-enyl)-dodeca-5,9-dienyl]-[1,3]dioxolane