N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide
• CAS No.: 1228644-06-1
• Molecular Formula: C₁₉H₂₃N₃O₄S
• Molecular Weight: 389.475
• Mol file: 1228644-06-1.mol

Synonyms:N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide

Chemical Property of N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide

There total 1 articles about N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

C16H19N3O4S (1207383-25-2) + allyl bromide (106-95-6) → N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide (1228644-06-1)

Guidance literature:

With potassium carbonate; In acetone; for 4h; Reflux;

DOI:10.1055/s-0029-1219228

Reference yield: 90.0%

N-allyl-N-(6-allyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methylbenzenesulfonamide (1228644-06-1) → 1,3-dimethyl-5-tosyl-5,6-dihydro-1H-pyrimido[5,4-b]azepine-2,4(3H,9H)-dione (1228644-17-4)

Guidance literature:

With Grubbs catalyst first generation; In dichloromethane; at 25 ℃; for 10h; Inert atmosphere;

DOI:10.1055/s-0029-1219228

upstream raw materials:

C₁₆H₁₉N₃O₄S

allyl bromide

Downstream raw materials:

1,3-dimethyl-5-tosyl-5,6-dihydro-1H-pyrimido[5,4-b]azepine-2,4(3H,9H)-dione