3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one

Base Information

Chemical Name:3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one
CAS No.:13220-44-5
Molecular Formula:C15H12 N2 O3
Molecular Weight:268.272
Hs Code.:
NSC Number:115618
DSSTox Substance ID:DTXSID80297335
ChEMBL ID:CHEMBL1981394

Synonyms:13220-44-5;3-(4-nitrobenzyl)-1,3-dihydro-2h-indol-2-one;NSC115618;CHEMBL1981394;DTXSID80297335;NSC-115618;NCI60_000352

Suppliers and Price of 3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one

Chemical Property:

Vapor Pressure:1.26E-09mmHg at 25°C
Boiling Point:486.8°Cat760mmHg
Flash Point:248.2°C
Density:1.333g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:268.08479225
Heavy Atom Count:20
Complexity:385

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C(=O)N2)CC3=CC=C(C=C3)[N+](=O)[O-]

Technology Process of 3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one

There total 2 articles about 3-(4-Nitrobenzyl)-1,3-dihydro-2h-indol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59-48-3
2-oxoindole

: 555-16-8
4-nitrobenzaldehdye

: 13220-44-5
3-(4-nitrobenzyl)indolin-2-one

Guidance literature:: 2-oxoindole; 4-nitrobenzaldehdye; With pyrrolidine; In ethanol; for 2h; Reflux;

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 2h;
DOI:10.1002/adsc.201800877

Reference yield:

: 13220-44-5
3-(4-nitrobenzyl)indolin-2-one

Guidance literature:: Oxindol, 4-Nitro-benzylchlorid, ethanol. Natriumethylat, A.;
DOI:10.1016/S0040-4020(01)92520-7

Reference yield: 98.0%

: 13220-44-5
3-(4-nitrobenzyl)indolin-2-one

: 66003-76-7
Diphenyliodonium triflate

: (R)-3-(4-nitrobenzyl)-3-phenylindolin-2-one

Guidance literature:: 3-(4-nitrobenzyl)indolin-2-one; With C₃₉H₄₄N₄O₄; scandium tris(trifluoromethanesulfonate); In dichloromethane; at 35 ℃; for 0.5h; Inert atmosphere; Molecular sieve;

Diphenyliodonium triflate; With sodium hydrogencarbonate; In dichloromethane; at 35 ℃; for 48h; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.201303602