N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

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Chemical Name:N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine
CAS No.:1194510-06-9
Molecular Formula:C₁₈H₂₈N₂O₃
Molecular Weight:320.432
Hs Code.:

Synonyms:N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

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Chemical Property of N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

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Technology Process of N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

There total 1 articles about N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 1194509-73-3
N-[3-(3,4-dimethoxyphenyl)propylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

: 1194510-06-9
N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

Guidance literature:: N-[3-(3,4-dimethoxyphenyl)propylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 - 0 ℃; Inert atmosphere;

methyl halide; In tetrahydrofuran; hexane; at -90 - 20 ℃; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1016/j.tetasy.2009.07.015

Reference yield:

: 1194510-06-9
N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine

: C₁₈H₃₀N₂O₃

Guidance literature:: N-[(R)-3-(3,4-dimethoxyphenyl)-2-methylpropylidene]-[(S)-2-methoxymethylpyrrolidin-1-yl]amine; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; Reflux;

With water; sodium hydroxide; In tetrahydrofuran;
DOI:10.1016/j.tetasy.2009.07.015