4-[(3-Chlorophenoxy)methyl]benzoic acid

Base Information

Chemical Name:4-[(3-Chlorophenoxy)methyl]benzoic acid
CAS No.:149288-39-1
Molecular Formula:C₁₄H₁₁ClO₃
Molecular Weight:262.693
Hs Code.:
DSSTox Substance ID:DTXSID801280457
ChEMBL ID:CHEMBL4586350
Mol file:149288-39-1.mol

Synonyms:4-[(3-Chlorophenoxy)methyl]benzoic acid;149288-39-1;4-((3-Chlorophenoxy)methyl)benzoic acid;4-(3-chlorophenoxymethyl)benzoic acid;4-(3-Chloro-phenoxymethyl)-benzoic acid;CHEMBL4586350;MFCD02090855;SCHEMBL694229;DTXSID801280457;ZFA28839;BBL038706;BDBM50508805;STK312442;AKOS000263230;FS-5825;4-((3-Chlorophenoxy)methyl)benzoicacid;NCGC00340395-01;Benzoic acid, 4-(3-chlorophenoxymethyl)-;4-[(3-Chlorophenoxy)methyl]benzoic acid #;CS-0269230;EN300-83485;AB01333198-02

Suppliers and Price of 4-[(3-Chlorophenoxy)methyl]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
4-(3-Chloro-phenoxymethyl)-benzoicacid
100mg
$ 80.00

Oakwood
4-(3-Chloro-phenoxymethyl)-benzoicacid
1g
$ 480.00

Crysdot
4-((3-Chlorophenoxy)methyl)benzoicacid 95+%
1g
$ 470.00

CHESS?
CA001026:4-(3-Chloro-phenoxymethyl)-benzoicacid 95
1 g
$ 336.00

Total 5 raw suppliers

Chemical Property of 4-[(3-Chlorophenoxy)methyl]benzoic acid

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:262.0396719
Heavy Atom Count:18
Complexity:274

Purity/Quality:

99% ^*data from raw suppliers

4-(3-Chloro-phenoxymethyl)-benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)OCC2=CC=C(C=C2)C(=O)O

Technology Process of 4-[(3-Chlorophenoxy)methyl]benzoic acid

There total 5 articles about 4-[(3-Chlorophenoxy)methyl]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: ethyl 4-([3-chlorophenoxy]methyl)benzoate

: 149288-39-1
4-([3-chlorophenoxy]methyl)benzoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran;
DOI:10.1021/acsmedchemlett.8b00551

Reference yield:

: 99-94-5
p-Toluic acid

: 149288-39-1
4-([3-chlorophenoxy]methyl)benzoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / Reflux

2: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / chloroform / 1 h / Inert atmosphere; Reflux

3: potassium carbonate / N,N-dimethyl-formamide

4: lithium hydroxide; water / tetrahydrofuran

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sulfuric acid; water; potassium carbonate; lithium hydroxide; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; 3: |Williamson Ether Synthesis;
DOI:10.1021/acsmedchemlett.8b00551

Reference yield:

: 94-08-6
4-methylbenzoic acid ethyl ester

: 149288-39-1
4-([3-chlorophenoxy]methyl)benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / chloroform / 1 h / Inert atmosphere; Reflux

2: potassium carbonate / N,N-dimethyl-formamide

3: lithium hydroxide; water / tetrahydrofuran

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); water; potassium carbonate; lithium hydroxide; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; 2: |Williamson Ether Synthesis;
DOI:10.1021/acsmedchemlett.8b00551