6-Fluoroquinolin-2(1H)-one

Base Information

Chemical Name:6-Fluoroquinolin-2(1H)-one
CAS No.:22614-75-1
Molecular Formula:C₉H₆FNO
Molecular Weight:163.151
Hs Code.:2933790090
DSSTox Substance ID:DTXSID20431438
Wikidata:Q82245313
Mol file:22614-75-1.mol

Synonyms:6-FLUOROQUINOLIN-2(1H)-ONE;22614-75-1;6-fluoro-1H-quinolin-2-one;6-Fluoroquinolin-2-ol;6-fluoro-1,2-dihydroquinolin-2-one;MFCD08236766;6-fluorocarbostyril;2(1H)-Quinolinone,6-fluoro-;6-fluoroquinolone;6-FLUORO-2-HYDROXYQUINOLINE;SCHEMBL607156;SCHEMBL9192758;DTXSID20431438;CJVMYPHDEMEFEM-UHFFFAOYSA-N;AMY33227;AKOS013465537;AB43955;AS-59565;CS-0046872;EN300-625028

Suppliers and Price of 6-Fluoroquinolin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Fluoroquinolin-2(1H)-one
1g
$ 130.00

SynQuest Laboratories
6-Fluoro-1,2-dihydroquinolin-2-one 96%
1 g
$ 184.00

SynQuest Laboratories
6-Fluoro-1,2-dihydroquinolin-2-one 96%
250 mg
$ 88.00

J&W Pharmlab
6-Fluoro-1H-quinolin-2-one 97%
1g
$ 80.00

Crysdot
6-Fluoroquinolin-2(1H)-one 95+%
25g
$ 847.00

Crysdot
6-Fluoroquinolin-2(1H)-one 95+%
10g
$ 470.00

ChemScene
6-Fluoroquinolin-2(1H)-one
1g
$ 147.00

Chemenu
6-Fluoro-1H-quinolin-2-one 95%
25g
$ 800.00

Chemenu
6-Fluoro-1H-quinolin-2-one 95%
10g
$ 445.00

Apolloscientific
6-Fluoroquinolin-2(1H)-one 98%
5g
$ 300.00

Total 23 raw suppliers

Chemical Property of 6-Fluoroquinolin-2(1H)-one

Chemical Property:

Melting Point:270-275 °C
Boiling Point:341.206 °C at 760 mmHg
PKA:10.58±0.70(Predicted)
Flash Point:160.156 °C
PSA：32.86000
Density:1.292 g/cm³
LogP:1.66720
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:163.043341977
Heavy Atom Count:12
Complexity:227

Purity/Quality:

99%, ^*data from raw suppliers

6-Fluoroquinolin-2(1H)-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=O)N2)C=C1F

Technology Process of 6-Fluoroquinolin-2(1H)-one

There total 15 articles about 6-Fluoroquinolin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 396-30-5
6-fluoroquinoline

: 22614-75-1
6-fluoro-1H-quinolin-2-one

Guidance literature:: With water; chloroacetic acid ethyl ester; In ethyl acetate; for 0.5h; Microwave irradiation;

Reference yield: 89.0%

: 2338-74-1
6-fluoroquinoline N--oxide

: 22614-75-1
6-fluoro-1H-quinolin-2-one

Guidance literature:: With 1,8-dimethoxy-10-phenyl-9-(o-tolyl)acridin-10-ium chloride; In dimethyl sulfoxide; at 20 ℃; for 8h; Irradiation; Green chemistry;
DOI:10.1039/d1gc01460a