Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Base Information

Chemical Name:Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate
CAS No.:144727-58-2
Molecular Formula:C₂₂H₂₃BrF₂N₂O₂
Molecular Weight:465.338
Hs Code.:

Synonyms:Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Suppliers and Price of Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

There total 5 articles about Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 364-74-9
1,4-difluoro-2-nitrobenzene

: 144727-58-2
Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / potassium carbonate / tetrahydrofuran / 8 h / Heating

2: 88 percent / H₂ / Raney nickel / tetrahydrofuran / Ambient temperature

3: triethylamine / CHCl₃ / 2 h / Ambient temperature

With hydrogen; potassium carbonate; triethylamine; nickel; In tetrahydrofuran; chloroform;

Reference yield:

: 112734-22-2
4-bromo-2-fluorobenzylamine

: 144727-58-2
Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / potassium carbonate / tetrahydrofuran / 8 h / Heating

2: 88 percent / H₂ / Raney nickel / tetrahydrofuran / Ambient temperature

3: triethylamine / CHCl₃ / 2 h / Ambient temperature

With hydrogen; potassium carbonate; triethylamine; nickel; In tetrahydrofuran; chloroform;

Reference yield:

: 144727-99-1
(4-Bromo-2-fluoro-benzyl)-(4-fluoro-2-nitro-phenyl)-amine

: 144727-58-2
Ethyl 4-[1-(2-fluoro-4-bromobenzyl)-5flurobenzimidazol-2-yl]-3,3-dimethylbutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / H₂ / Raney nickel / tetrahydrofuran / Ambient temperature

2: triethylamine / CHCl₃ / 2 h / Ambient temperature

With hydrogen; triethylamine; nickel; In tetrahydrofuran; chloroform;